3SOB6_DENVI
ID 3SOB6_DENVI Reviewed; 60 AA.
AC P01405;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Toxin 4.9.6;
OS Dendroaspis viridis (Western green mamba).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Dendroaspis.
OX NCBI_TaxID=8621;
RN [1]
RP PROTEIN SEQUENCE, TOXIC DOSE, AND SUBCELLULAR LOCATION.
RC TISSUE=Venom;
RX PubMed=4442418; DOI=10.1111/j.1432-1033.1974.tb03845.x;
RA Shipolini R.A., Banks B.E.C.;
RT "The amino-acid sequence of a polypeptide from the venom of Dendroaspis
RT viridis.";
RL Eur. J. Biochem. 49:399-405(1974).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:4442418}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC -!- TOXIC DOSE: LD(50) is >3.3 mg/kg by intraperitoneal injection.
CC {ECO:0000269|PubMed:4442418}.
CC -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC subfamily. Orphan group XI sub-subfamily. {ECO:0000305}.
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DR PIR; A01676; T5EP2V.
DR AlphaFoldDB; P01405; -.
DR SMR; P01405; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.60.10; -; 1.
DR InterPro; IPR045860; Snake_toxin-like_sf.
DR InterPro; IPR018354; Snake_toxin_con_site.
DR SUPFAM; SSF57302; SSF57302; 1.
DR PROSITE; PS00272; SNAKE_TOXIN; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT CHAIN 1..60
FT /note="Toxin 4.9.6"
FT /evidence="ECO:0000269|PubMed:4442418"
FT /id="PRO_0000093664"
FT DISULFID 3..22
FT /evidence="ECO:0000250|UniProtKB:P0C1Z0"
FT DISULFID 17..38
FT /evidence="ECO:0000250|UniProtKB:P0C1Z0"
FT DISULFID 40..52
FT /evidence="ECO:0000250|UniProtKB:P0C1Z0"
FT DISULFID 53..58
FT /evidence="ECO:0000250|UniProtKB:P0C1Z0"
SQ SEQUENCE 60 AA; 6800 MW; 291E62A51D3DF72B CRC64;
MICYSHKTPQ NSATITCEEK TCYKFVTKLP GVILARGCGC PKKEIFRKSI HCCRSDKCNE