ANR52_CHICK
ID ANR52_CHICK Reviewed; 1073 AA.
AC Q5ZLC8;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C;
DE Short=PP6-ARS-C;
DE Short=Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C;
GN Name=ANKRD52; ORFNames=RCJMB04_6l3;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Putative regulatory subunit of protein phosphatase 6 (PP6)
CC that may be involved in the recognition of phosphoprotein substrates.
CC {ECO:0000250}.
CC -!- SUBUNIT: Protein phosphatase 6 (PP6) holoenzyme is proposed to be a
CC heterotrimeric complex formed by the catalytic subunit, a SAPS domain-
CC containing subunit (PP6R) and an ankyrin repeat-domain containing
CC regulatory subunit (ARS). {ECO:0000250}.
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DR EMBL; AJ719806; CAG31465.1; -; mRNA.
DR RefSeq; NP_001012957.1; NM_001012939.1.
DR AlphaFoldDB; Q5ZLC8; -.
DR SMR; Q5ZLC8; -.
DR STRING; 9031.ENSGALP00000023054; -.
DR PaxDb; Q5ZLC8; -.
DR GeneID; 426469; -.
DR KEGG; gga:426469; -.
DR CTD; 283373; -.
DR VEuPathDB; HostDB:geneid_426469; -.
DR eggNOG; KOG0504; Eukaryota.
DR eggNOG; KOG0512; Eukaryota.
DR InParanoid; Q5ZLC8; -.
DR OrthoDB; 1115202at2759; -.
DR PhylomeDB; Q5ZLC8; -.
DR PRO; PR:Q5ZLC8; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0030315; C:T-tubule; IBA:GO_Central.
DR GO; GO:0036371; P:protein localization to T-tubule; IBA:GO_Central.
DR GO; GO:0055117; P:regulation of cardiac muscle contraction; IBA:GO_Central.
DR Gene3D; 1.25.40.20; -; 10.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 8.
DR Pfam; PF13637; Ank_4; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 28.
DR SUPFAM; SSF48403; SSF48403; 3.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 21.
PE 2: Evidence at transcript level;
KW ANK repeat; Reference proteome; Repeat.
FT CHAIN 1..1073
FT /note="Serine/threonine-protein phosphatase 6 regulatory
FT ankyrin repeat subunit C"
FT /id="PRO_0000244589"
FT REPEAT 7..36
FT /note="ANK 1"
FT REPEAT 40..69
FT /note="ANK 2"
FT REPEAT 73..102
FT /note="ANK 3"
FT REPEAT 106..135
FT /note="ANK 4"
FT REPEAT 139..168
FT /note="ANK 5"
FT REPEAT 172..201
FT /note="ANK 6"
FT REPEAT 205..234
FT /note="ANK 7"
FT REPEAT 238..267
FT /note="ANK 8"
FT REPEAT 271..301
FT /note="ANK 9"
FT REPEAT 305..334
FT /note="ANK 10"
FT REPEAT 338..367
FT /note="ANK 11"
FT REPEAT 371..400
FT /note="ANK 12"
FT REPEAT 422..451
FT /note="ANK 13"
FT REPEAT 455..484
FT /note="ANK 14"
FT REPEAT 488..544
FT /note="ANK 15"
FT REPEAT 548..578
FT /note="ANK 16"
FT REPEAT 583..612
FT /note="ANK 17"
FT REPEAT 616..645
FT /note="ANK 18"
FT REPEAT 650..679
FT /note="ANK 19"
FT REPEAT 686..715
FT /note="ANK 20"
FT REPEAT 719..748
FT /note="ANK 21"
FT REPEAT 752..781
FT /note="ANK 22"
FT REPEAT 789..818
FT /note="ANK 23"
FT REPEAT 821..851
FT /note="ANK 24"
FT REPEAT 856..885
FT /note="ANK 25"
FT REPEAT 889..919
FT /note="ANK 26"
FT REPEAT 923..952
FT /note="ANK 27"
FT REPEAT 959..988
FT /note="ANK 28"
SQ SEQUENCE 1073 AA; 115863 MW; ABBF9E1FA801CE46 CRC64;
MGILSITDQP PLVQAIFNRD VEEVRSLLNQ KENINVLDQE RRTPLHTAAY IGDVAILELL
ILSGANVNAK DTVWLTPLHR AAASRNEKAL HLLLKHSADV NARDKYWQTP LHVAAANRAT
KCVEAIIPLL STVNVADRTG RTALHHAVHS GHLEMVNLLL NKGASLSTCD KKDRQPIHWA
AFLGHLEVLK LLVARGADVM CKDKKGYTLL HTAAASGQIE VVRHLLRLGV EIDEPNSFGN
TALHIACYMG QDAVANELVN YGANVNQPNE KGFTPLHFAA VSTNGALCLE LLVNNGADVN
FQSKEGKSPL HMAAIHGRFT RSQILIQNGS EIDCADKYGN TPLHVAARYG HELLISTLMT
NGADTARRGI HDMFPLHLAV LFGFSDCCRK LLSSGQLYSI VSSLSNEHVL SAGFDINTPD
NLGRTCLHAA ASGGNVECLN LLLSSGADLR RRDKFGRTPL HYAAANGSYQ CTVTLVTAGA
SINEADCKGC TPLHYAAASD TYRRAETHSG NSHDTDEEPL KESRMKEAFF CLEFLLDNGA
DPSLRDKQGY TAVHYAAAYG NRQNLELLLE MSFNCLEDVE STIPVSPLHL AAYNGHCEAL
KTLAETLVNL DVRDHKGRTA LYLATERGST ECVEVLTSHG ASALVKERKR KWTPLHAAAA
NGNTDSLHLL IDSGERADIT DVMDIHGQTP LMLAIMNGHV DCVHLLLEKG STADAADKRG
RTALHRGAVT GCEDCLAALL DHDAFVLCRD FKGRTPIHFA SACGHLEILR TLLQAALSTD
PLDSVVDYSG YSPMHWASYS GHEDCLELLL EHNPFAYLEG NPFTPLHCAV INNQDSTAEM
LVEALGAKIV NSRDAKGRTP LHAAAFADNI HGLQLLLRHQ AEVDTTDKLG RTPLMMASEN
GHTAAVEFLL YQAKANITVL DVNKNTALHL ACSKGHEKCA LLILGETQDL GLINASNSAL
QMPLHIAARN GLATVVQALL SRGATVLAVD EEGHTPALAC APNKDVADCL ALILSTMKPF
PPKDAISSFS FNLLKNCGIA AKTAACGALP NGSTCPYSKD RHNAIGLDGC YSE
