ID   ANR52_DANRE             Reviewed;        1071 AA.
AC   Q502K3;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C;
DE            Short=PP6-ARS-C;
DE            Short=Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C;
GN   Name=ankrd52; ORFNames=zgc:112069;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative regulatory subunit of protein phosphatase 6 (PP6)
CC       that may be involved in the recognition of phosphoprotein substrates.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Protein phosphatase 6 (PP6) holoenzyme is proposed to be a
CC       heterotrimeric complex formed by the catalytic subunit, a SAPS domain-
CC       containing subunit (PP6R) and an ankyrin repeat-domain containing
CC       regulatory subunit (ARS). {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC095664; AAH95664.1; -; mRNA.
DR   RefSeq; NP_001018164.1; NM_001018154.1.
DR   AlphaFoldDB; Q502K3; -.
DR   SMR; Q502K3; -.
DR   BioGRID; 95949; 1.
DR   STRING; 7955.ENSDARP00000030948; -.
DR   PaxDb; Q502K3; -.
DR   PRIDE; Q502K3; -.
DR   GeneID; 553206; -.
DR   KEGG; dre:553206; -.
DR   CTD; 553206; -.
DR   ZFIN; ZDB-GENE-050522-247; ankrd52a.
DR   eggNOG; KOG0504; Eukaryota.
DR   InParanoid; Q502K3; -.
DR   OrthoDB; 1115202at2759; -.
DR   PhylomeDB; Q502K3; -.
DR   PRO; PR:Q502K3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   Gene3D; 1.25.40.20; -; 10.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   Pfam; PF00023; Ank; 2.
DR   Pfam; PF12796; Ank_2; 9.
DR   Pfam; PF13857; Ank_5; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 29.
DR   SUPFAM; SSF48403; SSF48403; 3.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 21.
PE   2: Evidence at transcript level;
KW   ANK repeat; Reference proteome; Repeat.
FT   CHAIN           1..1071
FT                   /note="Serine/threonine-protein phosphatase 6 regulatory
FT                   ankyrin repeat subunit C"
FT                   /id="PRO_0000244590"
FT   REPEAT          7..36
FT                   /note="ANK 1"
FT   REPEAT          40..69
FT                   /note="ANK 2"
FT   REPEAT          73..102
FT                   /note="ANK 3"
FT   REPEAT          106..135
FT                   /note="ANK 4"
FT   REPEAT          139..168
FT                   /note="ANK 5"
FT   REPEAT          172..201
FT                   /note="ANK 6"
FT   REPEAT          205..234
FT                   /note="ANK 7"
FT   REPEAT          238..267
FT                   /note="ANK 8"
FT   REPEAT          271..301
FT                   /note="ANK 9"
FT   REPEAT          305..334
FT                   /note="ANK 10"
FT   REPEAT          338..367
FT                   /note="ANK 11"
FT   REPEAT          371..400
FT                   /note="ANK 12"
FT   REPEAT          422..451
FT                   /note="ANK 13"
FT   REPEAT          455..484
FT                   /note="ANK 14"
FT   REPEAT          488..539
FT                   /note="ANK 15"
FT   REPEAT          543..573
FT                   /note="ANK 16"
FT   REPEAT          578..607
FT                   /note="ANK 17"
FT   REPEAT          611..640
FT                   /note="ANK 18"
FT   REPEAT          645..674
FT                   /note="ANK 19"
FT   REPEAT          681..710
FT                   /note="ANK 20"
FT   REPEAT          714..743
FT                   /note="ANK 21"
FT   REPEAT          747..776
FT                   /note="ANK 22"
FT   REPEAT          784..814
FT                   /note="ANK 23"
FT   REPEAT          816..845
FT                   /note="ANK 24"
FT   REPEAT          852..881
FT                   /note="ANK 25"
FT   REPEAT          885..915
FT                   /note="ANK 26"
FT   REPEAT          919..951
FT                   /note="ANK 27"
FT   REPEAT          955..984
FT                   /note="ANK 28"
SQ   SEQUENCE   1071 AA;  114430 MW;  60D33E9EDFC11193 CRC64;
     MGVLNISDQP PLVQAIFNRN ADEVKLFLHK KDEVNALDQE RRTPLHAAAW LGDVHIMDLL
     ISAGANVNAK DHVWLTPLHR AAASRNERAV GLLLRKGADV TARDKYWQTP LHIAAANRAT
     RCVETLLPHV SSLNMADRTG RAPLHHAAQS GYQEMVKLLL NKGANLSASD KKDRQPIHWA
     AYLGHLEVVK LLVSQGSDKS CKDKRGYTPL HAAAASGHVD VVKYLLRNGA EIDEPNAFGN
     TALHVACYTG QEAVANELVN RGANVNQPNH RGYTPLHLAA VSTNGALCLE LLVNNGADVN
     MQSKEGKSPL HMAAIHGRFT RSQILIQNGG EIDCVDRYGN TPLHVAAKYG HELLISTLMT
     NGADTARQGI HGMFPLHLAV LYGSSDCCRK LLSSGQLYSI VLSMSKEHVL SAGFDINTPD
     NFGRTCLHAA ASGGNIECLN LLLSSGADMN KKDKFGRTPL HYAAANGRYQ CVVVLVGAGA
     EVNERDRSGC TPLHYSAAST AFCRTDRPHA STHQNQEDGE KESFLCVEHL LDNGADPCLC
     NTKGYSAVHY AAAHGNKQNL ELLLEMCFNT LGDKESNGSI SPLHLAVESG HWECVTVLIE
     SGVCVDVCDP VGRSVLYLAS QRGHSRCVEL LLSQSASCLL AEHRSKWGPL HVAAANGHSE
     CLRMLLCSEG GADLVNVTDA EGQTPLMLAV LGGHTDCVHL LLERGACPDM KDRRGRTALH
     RGAVMGREDC LTALLSHNVS VLSRDFQGRS ALHLAASCGH ADILSNLLSA ADHSQPQDPL
     TDRHGYTPAH WAAYHGHEDC LEVLLELKPC SIQEGNPFTP LHCALINGHS GSAELLLESS
     VCNSLVNIRD AKGRTPLHAA AVAEDVAGLQ LVLRQGADID AVDHSGRSAL MVAADYGQSG
     AVALLLHRAK ADLSLLDVNK NTALHLACSK AHEMCAMLIL KEIHNPILIN ATNSMLQMPL
     HIAARNGLAT VVQALLNRGA TVLAVDEEGH TPALACASNK AVADCLALIL STMKPSSSTA
     SSSSPSSPSL NLLKHCGITA ACPPLPNGGL RHGYGKDRHG ATIGLDGCLT E