ID   ANR54_DANRE             Reviewed;         315 AA.
AC   Q6DGX3;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Ankyrin repeat domain-containing protein 54;
GN   Name=ankrd54; ORFNames=zgc:110569, zgc:92735;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB; TISSUE=Embryo, and Liver;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in regulating intracellular signaling
CC       events associated with erythroid terminal differentiation.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Midbody {ECO:0000250}. Note=Shuttles between nucleus and cytoplasm
CC       during the cell cycle. {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC076214; AAH76214.1; -; mRNA.
DR   EMBL; BC092933; AAH92933.1; -; mRNA.
DR   EMBL; BC096993; AAH96993.1; -; mRNA.
DR   RefSeq; NP_001002578.1; NM_001002578.1.
DR   AlphaFoldDB; Q6DGX3; -.
DR   SMR; Q6DGX3; -.
DR   STRING; 7955.ENSDARP00000072599; -.
DR   PaxDb; Q6DGX3; -.
DR   Ensembl; ENSDART00000078137; ENSDARP00000072599; ENSDARG00000055743.
DR   GeneID; 436851; -.
DR   KEGG; dre:436851; -.
DR   CTD; 129138; -.
DR   ZFIN; ZDB-GENE-040718-318; ankrd54.
DR   eggNOG; KOG0504; Eukaryota.
DR   GeneTree; ENSGT00940000157805; -.
DR   HOGENOM; CLU_072816_0_0_1; -.
DR   InParanoid; Q6DGX3; -.
DR   OMA; DDMGNGA; -.
DR   OrthoDB; 1559479at2759; -.
DR   PhylomeDB; Q6DGX3; -.
DR   TreeFam; TF330790; -.
DR   PRO; PR:Q6DGX3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 3.
DR   Bgee; ENSDARG00000055743; Expressed in somite and 25 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   SMART; SM00248; ANK; 3.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   2: Evidence at transcript level;
KW   ANK repeat; Cytoplasm; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..315
FT                   /note="Ankyrin repeat domain-containing protein 54"
FT                   /id="PRO_0000274496"
FT   REPEAT          124..153
FT                   /note="ANK 1"
FT   REPEAT          157..186
FT                   /note="ANK 2"
FT   REPEAT          190..219
FT                   /note="ANK 3"
FT   REPEAT          223..255
FT                   /note="ANK 4"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   315 AA;  34335 MW;  2D6D963461E6F231 CRC64;
     MDGSSPLLAA AGSDGDRSSS EGEYTLAGGP SAGDTEKREG ESPMEAAGAG TVGFSISRLD
     TLSALRLNRT RPAADTELRY LHLLWKPGEL LQAGRSTPGK ITSSRVRRLA RARRNMGPIG
     KDLHAVKRLR EAANSNDIDT VRRLLEDDTD PCAADDKGRT ALHFSSCNGN ETIVQLLLSY
     GADPNQRDSL GNTPLHLAAC TNHVPVITTL LRGGARVDAL DRAGRTPLHL ARSKLNILQE
     GDSRSLETLR GEVTQIIQML REYLNIMGQS EEREKLEHIS TQLQNTRTRE QVDEVTDLLA
     SFTSLSIQMQ NMGDR