ID   ANSP1_MYCBO             Reviewed;         489 AA.
AC   Q7VEQ4; A0A1R3Y082; X2BJS3;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=L-asparagine permease 1;
DE   AltName: Full=L-asparagine transport protein 1;
GN   Name=ansP1; OrderedLocusNames=BQ2027_MB2151;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC       {ECO:0000305}.
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DR   EMBL; LT708304; SIU00758.1; -; Genomic_DNA.
DR   RefSeq; NP_855800.1; NC_002945.3.
DR   RefSeq; WP_010950662.1; NC_002945.4.
DR   AlphaFoldDB; Q7VEQ4; -.
DR   SMR; Q7VEQ4; -.
DR   EnsemblBacteria; SIU00758; SIU00758; BQ2027_MB2151.
DR   PATRIC; fig|233413.5.peg.2365; -.
DR   OMA; QVPYAGI; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR004841; AA-permease/SLC12A_dom.
DR   InterPro; IPR004840; Amoino_acid_permease_CS.
DR   Pfam; PF00324; AA_permease; 1.
DR   PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..489
FT                   /note="L-asparagine permease 1"
FT                   /id="PRO_0000054187"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        439..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   489 AA;  52535 MW;  93540871D2B63384 CRC64;
     MSAASQRVDA FGEEAGYHKG LKPRQLQMIG IGGAIGTGLF LGASGRLAKA GPGLFLVYGV
     CGVFVFLILR ALGELVLHRP SSGSFVSYAR EFFGEKAAYA VGWMYFLHWA MTSIVDTTAI
     ATYLQRWTIF TVVPQWILAL IALTVVLSMN LISVEWFGEL EFWAALIKVL ALMAFLVVGT
     VFLAGRYPVD GHSTGLSLWN NHGGLFPTSW LPLLIVTSGV VFAYSAVELV GTAAGETAEP
     EKIMPRAINS VVARIAIFYV GSVALLALLL PYTAYKAGES PFVTFFSKIG FHGAGDLMNI
     VVLTAALSSL NAGLYSTGRV MHSIAMSGSA PRFTARMSKS GVPYGGIVLT AVITLFGVAL
     NAFKPGEAFE IVLNMSALGI IAGWATIVLC QLRLHKLANA GIMQRPRFRM PFSPYSGYLT
     LLFLLVVLVT MASDKPIGTW TVATLIIVIP ALTAGWYLVR KRVMAVARER LGHTGPFPAV
     ANPPVRSRD