ANSP_SALTY
ID ANSP_SALTY Reviewed; 497 AA.
AC P40812;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=L-asparagine permease;
DE AltName: Full=L-asparagine transport protein;
GN Name=ansP; OrderedLocusNames=STM1584;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=SA2656;
RX PubMed=7894705; DOI=10.1099/00221287-141-1-141;
RA Jennings P.J., Andereson J.K., Beacham I.R.;
RT "Cloning and molecular analysis of the Salmonella enterica ansP gene,
RT encoding an L-asparagine permease.";
RL Microbiology 141:141-146(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC {ECO:0000305}.
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DR EMBL; U04851; AAA80001.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20502.1; -; Genomic_DNA.
DR RefSeq; NP_460543.1; NC_003197.2.
DR RefSeq; WP_000857101.1; NC_003197.2.
DR AlphaFoldDB; P40812; -.
DR SMR; P40812; -.
DR STRING; 99287.STM1584; -.
DR TCDB; 2.A.3.1.8; the amino acid-polyamine-organocation (apc) family.
DR PaxDb; P40812; -.
DR EnsemblBacteria; AAL20502; AAL20502; STM1584.
DR GeneID; 1253102; -.
DR KEGG; stm:STM1584; -.
DR PATRIC; fig|99287.12.peg.1675; -.
DR HOGENOM; CLU_007946_9_0_6; -.
DR OMA; QVPYAGI; -.
DR PhylomeDB; P40812; -.
DR BioCyc; SENT99287:STM1584-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR Pfam; PF00324; AA_permease; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..497
FT /note="L-asparagine permease"
FT /id="PRO_0000054186"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 353..373
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 378..398
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 422..442
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 497 AA; 54004 MW; BE80CB117992CBBD CRC64;
MKTQTTHAAE QHAAKRRWLN AHEEGYHKAM GNRQVQMIAI GGAIGTGLFL GAGARLQMAG
PALALVYLIC GIFSFFILRA LGELVLHRPS SGSFVSYARE FLGEKAAYVA GWMYFINWAM
TGIVDITAVA LYMHYWGAFG DVPQWVFALG ALTIVGTMNM IGVKWFAEME FWFALIKVLA
IVIFLVVGTI FLGTGQPLEG NATGFHLITD NGGFFPHGLL PALVLIQGVV FAFASIELVG
TAAGECKDPQ KMVPKAINSV IWRIGLFYVG SVVLLVLLLP WNAYQAGQSP FVTFFSKLGV
PYIGSIMNIV VLTAALSSLN SGLYCTGRIL RSMSMGGSAP KFMAKMSRQH VPYAGILATL
VVYVVGVFLN YLVPSRVFEI VLNFASLGII ASWAFIMVCQ MRLRQAIKEG KAADVSFKLP
GAPFTSWLTL LFLLSVLVLM AFDYPNGTYT IASLPLIAIL LVAGWFGVRR RVAEIHRTAP
VTADSTESVV LKEEAAT