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ANSP_SALTY
ID   ANSP_SALTY              Reviewed;         497 AA.
AC   P40812;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=L-asparagine permease;
DE   AltName: Full=L-asparagine transport protein;
GN   Name=ansP; OrderedLocusNames=STM1584;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SA2656;
RX   PubMed=7894705; DOI=10.1099/00221287-141-1-141;
RA   Jennings P.J., Andereson J.K., Beacham I.R.;
RT   "Cloning and molecular analysis of the Salmonella enterica ansP gene,
RT   encoding an L-asparagine permease.";
RL   Microbiology 141:141-146(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC       {ECO:0000305}.
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DR   EMBL; U04851; AAA80001.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20502.1; -; Genomic_DNA.
DR   RefSeq; NP_460543.1; NC_003197.2.
DR   RefSeq; WP_000857101.1; NC_003197.2.
DR   AlphaFoldDB; P40812; -.
DR   SMR; P40812; -.
DR   STRING; 99287.STM1584; -.
DR   TCDB; 2.A.3.1.8; the amino acid-polyamine-organocation (apc) family.
DR   PaxDb; P40812; -.
DR   EnsemblBacteria; AAL20502; AAL20502; STM1584.
DR   GeneID; 1253102; -.
DR   KEGG; stm:STM1584; -.
DR   PATRIC; fig|99287.12.peg.1675; -.
DR   HOGENOM; CLU_007946_9_0_6; -.
DR   OMA; QVPYAGI; -.
DR   PhylomeDB; P40812; -.
DR   BioCyc; SENT99287:STM1584-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR004841; AA-permease/SLC12A_dom.
DR   InterPro; IPR004840; Amoino_acid_permease_CS.
DR   Pfam; PF00324; AA_permease; 1.
DR   PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..497
FT                   /note="L-asparagine permease"
FT                   /id="PRO_0000054186"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        378..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        422..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        448..468
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   497 AA;  54004 MW;  BE80CB117992CBBD CRC64;
     MKTQTTHAAE QHAAKRRWLN AHEEGYHKAM GNRQVQMIAI GGAIGTGLFL GAGARLQMAG
     PALALVYLIC GIFSFFILRA LGELVLHRPS SGSFVSYARE FLGEKAAYVA GWMYFINWAM
     TGIVDITAVA LYMHYWGAFG DVPQWVFALG ALTIVGTMNM IGVKWFAEME FWFALIKVLA
     IVIFLVVGTI FLGTGQPLEG NATGFHLITD NGGFFPHGLL PALVLIQGVV FAFASIELVG
     TAAGECKDPQ KMVPKAINSV IWRIGLFYVG SVVLLVLLLP WNAYQAGQSP FVTFFSKLGV
     PYIGSIMNIV VLTAALSSLN SGLYCTGRIL RSMSMGGSAP KFMAKMSRQH VPYAGILATL
     VVYVVGVFLN YLVPSRVFEI VLNFASLGII ASWAFIMVCQ MRLRQAIKEG KAADVSFKLP
     GAPFTSWLTL LFLLSVLVLM AFDYPNGTYT IASLPLIAIL LVAGWFGVRR RVAEIHRTAP
     VTADSTESVV LKEEAAT
 
 
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