ANSP_STRCO
ID ANSP_STRCO Reviewed; 489 AA.
AC Q9X7P0;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=L-asparagine permease;
DE AltName: Full=L-asparagine transport protein;
GN Name=ansP; OrderedLocusNames=SCO6734; ORFNames=SC5F2A.17;
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145;
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC {ECO:0000305}.
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DR EMBL; AL939129; CAB40684.1; -; Genomic_DNA.
DR PIR; T35259; T35259.
DR RefSeq; NP_630807.1; NC_003888.3.
DR RefSeq; WP_011031143.1; NZ_VNID01000002.1.
DR AlphaFoldDB; Q9X7P0; -.
DR SMR; Q9X7P0; -.
DR STRING; 100226.SCO6734; -.
DR GeneID; 1102173; -.
DR KEGG; sco:SCO6734; -.
DR PATRIC; fig|100226.15.peg.6842; -.
DR eggNOG; COG1113; Bacteria.
DR HOGENOM; CLU_007946_9_0_11; -.
DR InParanoid; Q9X7P0; -.
DR PhylomeDB; Q9X7P0; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR Pfam; PF00324; AA_permease; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..489
FT /note="L-asparagine permease"
FT /id="PRO_0000054191"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 268..288
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 302..322
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 382..402
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 489 AA; 51797 MW; 219F74312E81F14C CRC64;
MSKDAVDTAQ VAAHPQATGT IPADAGDAGY SKDLKARHVN MIAIGGAIGT GLFLGAGGRL
RDAGPALAIA YLVAGVFAFF VVKALGELVL YRPSSGSFVS YAREFLGEKG AYVAGWMYFL
NWSTTGIADI TAIALYTHYW SMFTSIPQWV LALVALAVVL AVNLISVKIF GEMEFWFAIV
KVATLVGFML IGIFLLATQH EVSGQTPGMG MITDHGGILP HGVMPVVLVM QGVIFSYAAL
ELVGVAAGET AEPHKIVPRA VNSIMWRVAL FYVGSVVLLA LLLPSSLYSG DESPFVTVLS
GIGVPAAGDV MNLVVLTAAM SSLNSGLYST GRILRSMAMA GSAPRFTGVM SRSQVPYGGI
LLTCAVCVLG VGLNYLVPSK AFEIVLNVAS LGIISTWVII MICHLVFVRR ARAGLVERPG
FRLPGSPVTE IVTIAFLLAV VGLMWNDEEV GRKTVLLVPV IAVMLVAGWF GVRRRVAHQA
GQERPAPRE