ANTR6_ARATH
ID ANTR6_ARATH Reviewed; 517 AA.
AC Q3E9A0;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Probable anion transporter 6, chloroplastic;
DE AltName: Full=Phosphate transporter PHT4;5;
DE Flags: Precursor;
GN Name=ANTR6; Synonyms=PHT4;5; OrderedLocusNames=At5g20380;
GN ORFNames=F5O24.270;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14564522; DOI=10.1007/s00425-003-1121-5;
RA Roth C., Menzel G., Petetot J.M., Rochat-Hacker S., Poirier Y.;
RT "Characterization of a protein of the plastid inner envelope having
RT homology to animal inorganic phosphate, chloride and organic-anion
RT transporters.";
RL Planta 218:406-416(2004).
RN [5]
RP FUNCTION, TISSUE SPECIFICITY, AND SUBCELLULAR LOCATION.
RX PubMed=18086223; DOI=10.1111/j.1469-8137.2007.02331.x;
RA Guo B., Jin Y., Wussler C., Blancaflor E.B., Motes C.M., Versaw W.K.;
RT "Functional analysis of the Arabidopsis PHT4 family of intracellular
RT phosphate transporters.";
RL New Phytol. 177:889-898(2008).
RN [6]
RP TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=19513231; DOI=10.4161/psb.3.10.6666;
RA Guo B., Irigoyen S., Fowler T.B., Versaw W.K.;
RT "Differential expression and phylogenetic analysis suggest specialization
RT of plastid-localized members of the PHT4 phosphate transporter family for
RT photosynthetic and heterotrophic tissues.";
RL Plant Signal. Behav. 3:784-790(2008).
CC -!- FUNCTION: Inorganic phosphate and probable anion transporter.
CC {ECO:0000269|PubMed:18086223}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane
CC {ECO:0000269|PubMed:18086223}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:18086223}.
CC -!- TISSUE SPECIFICITY: Expressed in leaf veins and sepals.
CC {ECO:0000269|PubMed:18086223, ECO:0000269|PubMed:19513231}.
CC -!- INDUCTION: Expressed with a circadian rhythm showing a peak during the
CC middle of the day (under long day conditions).
CC {ECO:0000269|PubMed:19513231}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion
CC cotransporter (TC 2.A.1.14) family. {ECO:0000305}.
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DR EMBL; AF296825; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED92837.1; -; Genomic_DNA.
DR EMBL; AY095993; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_197538.2; NM_122045.4.
DR AlphaFoldDB; Q3E9A0; -.
DR SMR; Q3E9A0; -.
DR STRING; 3702.AT5G20380.1; -.
DR PaxDb; Q3E9A0; -.
DR PRIDE; Q3E9A0; -.
DR ProteomicsDB; 245057; -.
DR EnsemblPlants; AT5G20380.1; AT5G20380.1; AT5G20380.
DR GeneID; 832160; -.
DR Gramene; AT5G20380.1; AT5G20380.1; AT5G20380.
DR KEGG; ath:AT5G20380; -.
DR Araport; AT5G20380; -.
DR TAIR; locus:2149199; AT5G20380.
DR eggNOG; KOG2532; Eukaryota.
DR HOGENOM; CLU_001265_5_11_1; -.
DR InParanoid; Q3E9A0; -.
DR PhylomeDB; Q3E9A0; -.
DR PRO; PR:Q3E9A0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q3E9A0; baseline and differential.
DR Genevisible; Q3E9A0; AT.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009536; C:plastid; IDA:TAIR.
DR GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IDA:TAIR.
DR GO; GO:0006952; P:defense response; IEP:TAIR.
DR CDD; cd17380; MFS_SLC17A9_like; 1.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR044777; SLC17A9-like.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Transit peptide;
KW Transmembrane; Transmembrane helix.
FT TRANSIT 1..?
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN ?..517
FT /note="Probable anion transporter 6, chloroplastic"
FT /id="PRO_0000331539"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 170..190
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 397..417
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 484..504
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 51..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 56683 MW; 7C6FA411D47CC8F0 CRC64;
MARLTLRPHN HFFSSPIYAH KQPFLSVYTI FPHHHQNPLI KSRVKCSASG TERVRESKKL
PPKDPIEDPK PQLPIPEVLS TETGFEQNWP PWKNIPQRYK LIGATSLAFV ICNMDKVNLS
IAIIPMSHQF GWSSSVAGLV QSSFFWGYAL SQLPGGWLSK IFGGRKVLEI GVFTWSFATA
LVPLLAGFMP GLIFSRILVG IGEGVSPSAA TDLIARTIPV KERSRAVGFV FGGLSLGSVM
GLLLAPPIIE TFNWESVFYL FGLLGVGWFV GFQFLNEEEV SYKGNEISTS HKSENATKEE
LGSSLKEIPW KSFFQSPAVW AMIYTHFCGS WGHYTCLSWL PTYFSEALSL NLTEAAWVSI
LPPLASIVVT SLASQFADYL ITNGVDTTTV RKICQTIAFV APAICMTLSS VDIGLPPWEI
VGILTAGLAL SSFALSGLYC THQDISPEYA SILLGITNTV GAVPGIVGVA LTGFLLDSTH
SWTMSLFVPS IFFYLTGTVV WLAFASSEPQ TFRKEDS
