ANX10_MOUSE
ID ANX10_MOUSE Reviewed; 324 AA.
AC Q9QZ10; Q3TGJ1;
DT 21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Annexin A10;
DE AltName: Full=Annexin-10;
GN Name=Anxa10;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=10458909; DOI=10.1006/geno.1999.5895;
RA Morgan R.O., Jenkins N.A., Gilbert D.J., Copeland N.G., Balsara B.R.,
RA Testa J.R., Fernandez M.-P.;
RT "Novel human and mouse annexin A10 are linked to the genome duplications
RT during early chordate evolution.";
RL Genomics 60:40-49(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Stomach;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the annexin family. {ECO:0000255|PROSITE-
CC ProRule:PRU01245, ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ238978; CAB51927.1; -; mRNA.
DR EMBL; AK168715; BAE40557.1; -; mRNA.
DR EMBL; CH466569; EDL28663.1; -; Genomic_DNA.
DR EMBL; BC125319; AAI25320.1; -; mRNA.
DR EMBL; BC132207; AAI32208.1; -; mRNA.
DR CCDS; CCDS52558.1; -.
DR RefSeq; NP_001129561.1; NM_001136089.2.
DR AlphaFoldDB; Q9QZ10; -.
DR SMR; Q9QZ10; -.
DR STRING; 10090.ENSMUSP00000034052; -.
DR PhosphoSitePlus; Q9QZ10; -.
DR jPOST; Q9QZ10; -.
DR MaxQB; Q9QZ10; -.
DR PaxDb; Q9QZ10; -.
DR PRIDE; Q9QZ10; -.
DR ProteomicsDB; 281774; -.
DR Antibodypedia; 1612; 468 antibodies from 38 providers.
DR DNASU; 26359; -.
DR Ensembl; ENSMUST00000034052; ENSMUSP00000034052; ENSMUSG00000031635.
DR GeneID; 26359; -.
DR KEGG; mmu:26359; -.
DR UCSC; uc009lup.2; mouse.
DR CTD; 11199; -.
DR MGI; MGI:1347090; Anxa10.
DR VEuPathDB; HostDB:ENSMUSG00000031635; -.
DR eggNOG; KOG0819; Eukaryota.
DR GeneTree; ENSGT00940000160623; -.
DR HOGENOM; CLU_025300_0_0_1; -.
DR InParanoid; Q9QZ10; -.
DR OMA; KEIHDSW; -.
DR OrthoDB; 856254at2759; -.
DR PhylomeDB; Q9QZ10; -.
DR TreeFam; TF105452; -.
DR BioGRID-ORCS; 26359; 3 hits in 73 CRISPR screens.
DR PRO; PR:Q9QZ10; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q9QZ10; protein.
DR Bgee; ENSMUSG00000031635; Expressed in mucosa of stomach and 24 other tissues.
DR ExpressionAtlas; Q9QZ10; baseline and differential.
DR Genevisible; Q9QZ10; MM.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:InterPro.
DR Gene3D; 1.10.220.10; -; 4.
DR InterPro; IPR001464; Annexin.
DR InterPro; IPR018502; Annexin_repeat.
DR InterPro; IPR018252; Annexin_repeat_CS.
DR InterPro; IPR037104; Annexin_sf.
DR InterPro; IPR008156; ANX10.
DR Pfam; PF00191; Annexin; 4.
DR PRINTS; PR00196; ANNEXIN.
DR PRINTS; PR01809; ANNEXINX.
DR SMART; SM00335; ANX; 4.
DR SUPFAM; SSF47874; SSF47874; 1.
DR PROSITE; PS00223; ANNEXIN_1; 1.
DR PROSITE; PS51897; ANNEXIN_2; 4.
PE 2: Evidence at transcript level;
KW Annexin; Reference proteome; Repeat.
FT CHAIN 1..324
FT /note="Annexin A10"
FT /id="PRO_0000067508"
FT REPEAT 17..88
FT /note="Annexin 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01245"
FT REPEAT 89..160
FT /note="Annexin 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01245"
FT REPEAT 171..243
FT /note="Annexin 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01245"
FT REPEAT 247..318
FT /note="Annexin 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01245"
FT CONFLICT 29
FT /note="A -> R (in Ref. 1; CAB51927)"
FT /evidence="ECO:0000305"
FT CONFLICT 208
FT /note="W -> R (in Ref. 1; CAB51927)"
FT /evidence="ECO:0000305"
FT CONFLICT 222
FT /note="L -> M (in Ref. 1; CAB51927)"
FT /evidence="ECO:0000305"
FT CONFLICT 230
FT /note="Y -> T (in Ref. 1; CAB51927)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 324 AA; 37290 MW; 765B289819E0B4BE CRC64;
MFCGEYVQGT IFPAPNFNPM MDAQMLGGAL QGFDCNKDML IDILTQRSNA QRQMIAGTYQ
SMYGRDLISV LKEQLSSHFK EVMVGLMYPP PSYDAHELWH AMKGPGTDEN CLIEILASRT
NGEIFQMREA YCLQYSNNLQ EDIYSETSGH FRDTLMNLVQ ANREEGYSDP AMAAQDAMVL
WEACQQKTGE HKTMMQMILC NKSYPQLWLV FQEFQNISGQ DLVDAINDCY DGYFQELLVA
IVRCIQDKPS YFAYKLYRAI HDFGFHNKTV IRILIARSEI DLMTIRKRYK ERFGKSLFHD
IKNFASGHYE KALLAICAGD VEDY
