HKT14_ORYSJ
ID HKT14_ORYSJ Reviewed; 500 AA.
AC Q7XPF7; Q0JAB3; Q8L6H5;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 2.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Probable cation transporter HKT1;4 {ECO:0000303|PubMed:16809061};
DE Short=OsHKT1;4 {ECO:0000303|PubMed:16809061};
DE AltName: Full=Probable cation transporter HKT7 {ECO:0000303|PubMed:12795699};
DE Short=OsHKT7 {ECO:0000303|PubMed:12795699};
GN Name=HKT1;4 {ECO:0000303|PubMed:16809061};
GN Synonyms=HKT7 {ECO:0000303|PubMed:12795699};
GN OrderedLocusNames=Os04g0607600 {ECO:0000312|EMBL:BAS90913.1},
GN LOC_Os04g51830 {ECO:0000305};
GN ORFNames=OSJNBa0060N03.4 {ECO:0000312|EMBL:CAE03639.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=12795699; DOI=10.1046/j.1365-313x.2003.01764.x;
RA Garciadeblas B., Senn M.E., Banuelos M.A., Rodriguez-Navarro A.;
RT "Sodium transport and HKT transporters: the rice model.";
RL Plant J. 34:788-801(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16809061; DOI=10.1016/j.tplants.2006.06.001;
RA Platten J.D., Cotsaftis O., Berthomieu P., Bohnert H., Davenport R.J.,
RA Fairbairn D.J., Horie T., Leigh R.A., Lin H.X., Luan S., Maeser P.,
RA Pantoja O., Rodriguez-Navarro A., Schachtman D.P., Schroeder J.I.,
RA Sentenac H., Uozumi N., Very A.A., Zhu J.K., Dennis E.S., Tester M.;
RT "Nomenclature for HKT transporters, key determinants of plant salinity
RT tolerance.";
RL Trends Plant Sci. 11:372-374(2006).
CC -!- FUNCTION: Probable cation transporter. May be involved in regulation of
CC potassium-sodium homeostasis. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- DOMAIN: HKT transporters are proposed to contain 4 pore-forming regions
CC enclosed by transmembrane segments with each containing a potassium
CC channel-like selectivity filter motif. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family. HKT (TC
CC 2.A.38.3) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAE03639.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ491853; CAD37197.1; -; Genomic_DNA.
DR EMBL; AL606691; CAE03639.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008210; BAF15724.1; -; Genomic_DNA.
DR EMBL; AP014960; BAS90913.1; -; Genomic_DNA.
DR EMBL; AK109852; BAG98930.1; -; mRNA.
DR EMBL; AK120889; BAH00215.1; -; mRNA.
DR RefSeq; XP_015633970.1; XM_015778484.1.
DR AlphaFoldDB; Q7XPF7; -.
DR STRING; 4530.OS04T0607600-01; -.
DR PaxDb; Q7XPF7; -.
DR PRIDE; Q7XPF7; -.
DR EnsemblPlants; Os04t0607600-01; Os04t0607600-01; Os04g0607600.
DR GeneID; 4336927; -.
DR Gramene; Os04t0607600-01; Os04t0607600-01; Os04g0607600.
DR KEGG; osa:4336927; -.
DR eggNOG; KOG1341; Eukaryota.
DR HOGENOM; CLU_008384_2_0_1; -.
DR InParanoid; Q7XPF7; -.
DR OMA; RCWMLAG; -.
DR OrthoDB; 385384at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0008324; F:cation transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProt.
DR InterPro; IPR003445; Cat_transpt.
DR Pfam; PF02386; TrkH; 2.
PE 2: Evidence at transcript level;
KW Ion transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..500
FT /note="Probable cation transporter HKT1;4"
FT /id="PRO_0000070471"
FT TOPO_DOM 1..12
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 13..33
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 95..156
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 239..259
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 260..290
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 291..311
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 346..366
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 367..390
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 391..411
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 464..484
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 485..500
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 121..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 500 AA; 54239 MW; 815C4CCE5488652F CRC64;
MPTSRRALAG GALSMHVAYF LAISCLGYGL LGVLKVREPG AAPRRIDRFF TAVSAATVSS
MSTVEMEVFS NGQLVVLTVL MLLGGEVFVS LVGLASKWSK LRSDAMDRSR RVESHGDVAL
ADIDGGDVEN PTSSGEEAAS RRRPMDADTL RHNAVRALFY IVLAIFAVVH VVGAVAVAAY
VLASPGARRT LGDKSLNTWT FAVFTTVSTF SNCGFMPTNE NMVVFKRDAP LQLLLVPQVL
AGNTLFAPLL AACVWAAAAA TRREELVEMA REGGRAAAAG YAHLMPARRC WMLAATVAAF
VAVLMALVCG MEWGGALQGM SPWEKVVNAL FLAVNARHTG ESTVDLSILA PAILVLFVLM
MYLPPYTTWF PFEENSTTKD SNAENQGIRL LESTLLSQLS YLTIFVIAIC ITERRKLKED
PLNFSVLSIV VEVVSAYGNV GFSMGYSCSR QINPDHLCTD KWTGFVGRWS DSGKLILIFV
MFFGRLKKFS MKGGKAWKLS
