HKT23_ORYSJ
ID HKT23_ORYSJ Reviewed; 509 AA.
AC Q8L481; Q0JM66;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Probable cation transporter HKT2;3 {ECO:0000303|PubMed:16809061};
DE Short=OsHKT2;3 {ECO:0000303|PubMed:16809061};
DE AltName: Full=Probable cation transporter HKT3 {ECO:0000303|PubMed:12795699};
DE Short=OsHKT3 {ECO:0000303|PubMed:12795699};
GN Name=HKT2;3 {ECO:0000303|PubMed:16809061};
GN Synonyms=HKT3 {ECO:0000303|PubMed:12795699};
GN OrderedLocusNames=Os01g0532600 {ECO:0000312|EMBL:BAS72520.1},
GN LOC_Os01g34850 {ECO:0000305};
GN ORFNames=OJ1619_F12.15 {ECO:0000312|EMBL:BAD87687.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare; TISSUE=Shoot;
RX PubMed=12795699; DOI=10.1046/j.1365-313x.2003.01764.x;
RA Garciadeblas B., Senn M.E., Banuelos M.A., Rodriguez-Navarro A.;
RT "Sodium transport and HKT transporters: the rice model.";
RL Plant J. 34:788-801(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16809061; DOI=10.1016/j.tplants.2006.06.001;
RA Platten J.D., Cotsaftis O., Berthomieu P., Bohnert H., Davenport R.J.,
RA Fairbairn D.J., Horie T., Leigh R.A., Lin H.X., Luan S., Maeser P.,
RA Pantoja O., Rodriguez-Navarro A., Schachtman D.P., Schroeder J.I.,
RA Sentenac H., Uozumi N., Very A.A., Zhu J.K., Dennis E.S., Tester M.;
RT "Nomenclature for HKT transporters, key determinants of plant salinity
RT tolerance.";
RL Trends Plant Sci. 11:372-374(2006).
CC -!- FUNCTION: Probable cation transporter. May be involved in regulation of
CC potassium-sodium homeostasis. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- DOMAIN: HKT transporters are proposed to contain 4 pore-forming regions
CC enclosed by transmembrane segments with each containing a potassium
CC channel-like selectivity filter motif. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family. HKT (TC
CC 2.A.38.3) subfamily. {ECO:0000305}.
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DR EMBL; AJ491819; CAD37186.1; -; Genomic_DNA.
DR EMBL; AJ491820; CAD37187.1; -; mRNA.
DR EMBL; AP003447; BAD87687.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF05162.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS72520.1; -; Genomic_DNA.
DR RefSeq; XP_015632753.1; XM_015777267.1.
DR AlphaFoldDB; Q8L481; -.
DR SMR; Q8L481; -.
DR BioGRID; 796841; 1.
DR STRING; 4530.OS01T0532600-00; -.
DR PaxDb; Q8L481; -.
DR PRIDE; Q8L481; -.
DR EnsemblPlants; Os01t0532600-00; Os01t0532600-00; Os01g0532600.
DR GeneID; 4327804; -.
DR Gramene; Os01t0532600-00; Os01t0532600-00; Os01g0532600.
DR KEGG; osa:4327804; -.
DR eggNOG; KOG1341; Eukaryota.
DR HOGENOM; CLU_008384_2_0_1; -.
DR InParanoid; Q8L481; -.
DR OMA; CHEKAYN; -.
DR OrthoDB; 385384at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q8L481; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0008324; F:cation transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProt.
DR InterPro; IPR003445; Cat_transpt.
DR Pfam; PF02386; TrkH; 2.
PE 2: Evidence at transcript level;
KW Ion transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..509
FT /note="Probable cation transporter HKT2;3"
FT /id="PRO_0000070468"
FT TOPO_DOM 1..32
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 33..53
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..116
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 117..164
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..185
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..257
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 258..296
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..317
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 353..373
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 374..400
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 401..421
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 474..494
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 495..509
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 509 AA; 56374 MW; A620A676B6F34A0F CRC64;
MPIRLHIFVN SARHAINSSA FICRFIAYHL SPLLIHLSYF LIIDILGFVS LVVLRPSNHK
YNPRYVDMFF LSTSAVTVIG LATIQMEDLS SSQIAILTLL MFLDSKMFLS FLGLVLESSK
QNKHDPENRR VSSVTVCKQS QLEEATPQTP SMNSIDIKKR CLKYLVFVVL AYMIIILVTG
SLLVFMYIAH VSSARDVLTR KSINKALFSI SVTVSSFTNG GLLPTNESMV VFSSNNGLLL
LLIGQILAGS TLFPVFLRLV IWALRGLRLA KAEEPDFMMN NSSAVGFSHL LPNLQTIFLA
VVEVAFVAMT VILFCCLNWD SVVFAGLSSL QKITNALFMA VNARQAGENS IDCSLVAPAA
LVLFMVMMYT PSLTKLFSAC QDHKRIGPES DDRTSKGKPF LKMMAFSPLG FNTTVIMLVC
ITERRSLSTD PLNLSTFNII FEVISAYGNI GLSTGYSCSR QLQHQEGIAC HEKAYNFSGW
WSEPGKLILV LAMLCGRLNS KDSTSARTR
