ID   HLS1L_ARATH             Reviewed;         413 AA.
AC   O64815;
DT   18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Probable N-acetyltransferase HLS1-like;
DE            EC=2.3.1.-;
GN   OrderedLocusNames=At2g23060; ORFNames=F21P24.12;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=1;
CC         Comment=A number of isoforms are produced. According to EST
CC         sequences.;
CC       Name=1;
CC         IsoId=O64815-1; Sequence=Displayed;
CC   -!- SIMILARITY: Belongs to the acetyltransferase family. {ECO:0000305}.
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DR   EMBL; AC004401; AAC17822.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC07401.1; -; Genomic_DNA.
DR   EMBL; BT030057; ABN04795.1; -; mRNA.
DR   PIR; A84620; A84620.
DR   RefSeq; NP_179888.1; NM_127870.4. [O64815-1]
DR   AlphaFoldDB; O64815; -.
DR   BioGRID; 2189; 5.
DR   IntAct; O64815; 5.
DR   STRING; 3702.AT2G23060.1; -.
DR   iPTMnet; O64815; -.
DR   PaxDb; O64815; -.
DR   PRIDE; O64815; -.
DR   ProteomicsDB; 230247; -. [O64815-1]
DR   EnsemblPlants; AT2G23060.1; AT2G23060.1; AT2G23060. [O64815-1]
DR   GeneID; 816836; -.
DR   Gramene; AT2G23060.1; AT2G23060.1; AT2G23060. [O64815-1]
DR   KEGG; ath:AT2G23060; -.
DR   Araport; AT2G23060; -.
DR   TAIR; locus:2045329; AT2G23060.
DR   eggNOG; ENOG502QQCN; Eukaryota.
DR   HOGENOM; CLU_057213_0_0_1; -.
DR   InParanoid; O64815; -.
DR   OMA; GACEPLR; -.
DR   PhylomeDB; O64815; -.
DR   PRO; PR:O64815; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O64815; baseline and differential.
DR   Genevisible; O64815; AT.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   2: Evidence at transcript level;
KW   Acyltransferase; Alternative splicing; Reference proteome; Transferase.
FT   CHAIN           1..413
FT                   /note="Probable N-acetyltransferase HLS1-like"
FT                   /id="PRO_0000423404"
FT   DOMAIN          5..187
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
SQ   SEQUENCE   413 AA;  46111 MW;  8819D9A66FAF1975 CRC64;
     MTVLVEVREY DPSKDLATVE DVERRCEVGP AGKLSLFTDL LGDPICRVRH SPSYLMLVAE
     IGPKEKKELV GMIRGCIKTV TCGITTKRLD LTHNKSQNDV VITKPLYTKL AYILGLRVSP
     THRRQGIGFK LVKAMEDWFS QNGAEYSYFA TENDNHASVN LFTGKCGYAE FRTPSILVNP
     VYAHRVNISR RVTVIKLEPS DAELLYRLRF STTEFFPRDI DSVLNNKLSL GTFVAVPRGS
     CYGSGSRSWP GSAKFLEYPP DSWAVLSVWN CKDSFRLEVR GASRLRRVVS KATRMVDKTL
     PFLKIPSIPA VFRPFGLHFM YGIGGEGPRA EKMVKALCDH AHNLAKEGGC GVVAAEVAGE
     EPLRRGIPHW KVLSCAEDLW CIKRLGEDYS DGSVGDWTKS PPGDSIFVDP REF