ID   HLYC_RICCK              Reviewed;         298 AA.
AC   A8EZU0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Possible hemolysin C;
GN   Name=tlyC; OrderedLocusNames=A1E_04760;
OS   Rickettsia canadensis (strain McKiel).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; belli group.
OX   NCBI_TaxID=293613;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=McKiel;
RA   Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Dasch G., Eremeeva M.;
RT   "Complete genome sequence of Rickettsia canadensis.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- MISCELLANEOUS: It is not know if this bacteria is hemolytic.
CC   -!- SIMILARITY: Belongs to the UPF0053 family. Hemolysin C subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000409; ABV73873.1; -; Genomic_DNA.
DR   RefSeq; WP_012149068.1; NC_009879.1.
DR   AlphaFoldDB; A8EZU0; -.
DR   SMR; A8EZU0; -.
DR   STRING; 293613.A1E_04760; -.
DR   EnsemblBacteria; ABV73873; ABV73873; A1E_04760.
DR   KEGG; rcm:A1E_04760; -.
DR   eggNOG; COG1253; Bacteria.
DR   HOGENOM; CLU_015237_3_1_5; -.
DR   OMA; ERRHMAL; -.
DR   OrthoDB; 1155802at2; -.
DR   Proteomes; UP000007056; Chromosome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; -; 1.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   InterPro; IPR005170; Transptr-assoc_dom.
DR   Pfam; PF00571; CBS; 1.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   SMART; SM01091; CorC_HlyC; 1.
DR   SUPFAM; SSF54631; SSF54631; 1.
DR   SUPFAM; SSF56176; SSF56176; 1.
DR   PROSITE; PS51371; CBS; 2.
PE   3: Inferred from homology;
KW   CBS domain; Repeat.
FT   CHAIN           1..298
FT                   /note="Possible hemolysin C"
FT                   /id="PRO_0000319029"
FT   DOMAIN          80..141
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          145..202
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ   SEQUENCE   298 AA;  33673 MW;  FA6204F37010B433 CRC64;
     MFKSSKKEDS SKKNHNNKLI FAIRKLFSPI KNFFRQTKTP DNFFGVIKRL KINNQKMTLD
     ECNIFANLLK IKDKTIADIM VPRSDIAAIK LTTNLEELSE SIKLKVLHAR TLIYDGTLDN
     VVGFIHIKDL FKAFATKQNG CLKKLIRKHI IAAPSMKLLD LLTKMRRERT HIAIVVDEYG
     GTDGLVTIED LIEEIVGRID DEHDQQLDSD NLKVINNSTI ILNARVEVEV LEEIIGEKLK
     NDDEFDTIGG LVLTRVGSVP AIGTRINISE NIEIEVTDAT PRSLKQVKIR LKNALNSG