ID   HLYS3_HYDVD             Reviewed;         218 AA.
AC   Q52SK6;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Hydralysin-3;
GN   Name=Hln-3 {ECO:0000303|PubMed:15824108};
OS   Hydra viridissima (Green hydra) (Chlorohydra viridissima).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Aplanulata; Hydridae; Hydra.
OX   NCBI_TaxID=6082;
RN   [1] {ECO:0000305, ECO:0000312|EMBL:AAX89441.1}
RP   NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RX   PubMed=15824108; DOI=10.1074/jbc.m503242200;
RA   Sher D., Fishman Y., Zhang M., Lebendiker M., Gaathon A., Mancheno J.-M.,
RA   Zlotkin E.;
RT   "Hydralysins, a new category of beta-pore-forming toxins in cnidaria.";
RL   J. Biol. Chem. 280:22847-22855(2005).
CC   -!- FUNCTION: Does not induce flaccid paralysis when injected into blowfly
CC       larvae and lacks hemolytic activity. {ECO:0000269|PubMed:15824108}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q86LR2}.
CC   -!- SIMILARITY: Belongs to the hydralysin family. {ECO:0000305}.
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DR   EMBL; AY967765; AAX89441.1; -; mRNA.
DR   AlphaFoldDB; Q52SK6; -.
DR   SMR; Q52SK6; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Secreted; Toxin.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..218
FT                   /note="Hydralysin-3"
FT                   /id="PRO_0000221560"
SQ   SEQUENCE   218 AA;  23494 MW;  A26774B9DBC877B4 CRC64;
     MGKELLTFSD LRWLDSSPDT VRSAFTREYG TTPDGIALNS EGYFGYHSPP ITEQYGRPCY
     KQTGETKITS QDLSAPTDDV LGSSAAINRG DSPITLTFGV EGVFQMGGEF SLTVSVRKSG
     SSSVEKTSTS SVQVTVPPRS KVVVSMVGIM KKEKVFFEVP VTVDGSFGAN FSSTVQGHYF
     WFMDARSCLN KTSGVIKGTI DHANVFDVSV EVGPSEPL