HM01_CAEEL
ID HM01_CAEEL Reviewed; 132 AA.
AC P53547;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Homeobox protein ceh-1;
DE Flags: Fragment;
GN Name=ceh-1; ORFNames=F16H11.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-60.
RX PubMed=1978282; DOI=10.1093/nar/18.20.6101;
RA Hawkins N.C., McGhee J.D.;
RT "Homeobox containing genes in the nematode Caenorhabditis elegans.";
RL Nucleic Acids Res. 18:6101-6106(1990).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
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DR EMBL; FO080880; CCD67466.1; -; Genomic_DNA.
DR EMBL; X52810; CAB57215.1; ALT_SEQ; Genomic_DNA.
DR PIR; S13128; S13128.
DR PIR; T16081; T16081.
DR PIR; T37298; T37298.
DR RefSeq; NP_508796.2; NM_076395.4.
DR AlphaFoldDB; P53547; -.
DR SMR; P53547; -.
DR BioGRID; 56116; 4.
DR IntAct; P53547; 4.
DR STRING; 6239.F16H11.4; -.
DR PaxDb; P53547; -.
DR EnsemblMetazoa; F16H11.4.1; F16H11.4.1; WBGene00000428.
DR GeneID; 191614; -.
DR KEGG; cel:CELE_F16H11.4; -.
DR UCSC; F16H11.4; c. elegans.
DR CTD; 191614; -.
DR WormBase; F16H11.4; CE50450; WBGene00000428; ceh-1.
DR eggNOG; KOG0488; Eukaryota.
DR GeneTree; ENSGT00940000172282; -.
DR HOGENOM; CLU_134006_0_0_1; -.
DR InParanoid; P53547; -.
DR OrthoDB; 858478at2759; -.
DR PhylomeDB; P53547; -.
DR SignaLink; P53547; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00000428; Expressed in pharyngeal muscle cell (C elegans) and 2 other tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN <1..132
FT /note="Homeobox protein ceh-1"
FT /id="PRO_0000048981"
FT DNA_BIND 1..60
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 56..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
SQ SEQUENCE 132 AA; 14929 MW; E2959100BE76A5AD CRC64;
MRRARTAFTY EQLVALENKF KTSRYLSVVE RLNLAIQLQL SETQVKIWFQ NRRTKWKKHN
PGQDANTPQT PPSSDETQIQ PILPANPITS FSSLLLPPII SPANSAVLQG TSIPLTLFNL
NQILMPQNVG FN
