HM20A_CHICK
ID HM20A_CHICK Reviewed; 348 AA.
AC Q5ZKF4;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=High mobility group protein 20A;
DE AltName: Full=HMG box-containing protein 20A;
GN Name=HMG20A; ORFNames=RCJMB04_11c24;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Plays a role in neuronal differentiation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
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DR EMBL; AJ720130; CAG31789.1; -; mRNA.
DR RefSeq; NP_001025565.1; NM_001030394.1.
DR AlphaFoldDB; Q5ZKF4; -.
DR SMR; Q5ZKF4; -.
DR STRING; 9031.ENSGALP00000004319; -.
DR PaxDb; Q5ZKF4; -.
DR GeneID; 415346; -.
DR KEGG; gga:415346; -.
DR CTD; 10363; -.
DR VEuPathDB; HostDB:geneid_415346; -.
DR eggNOG; KOG0381; Eukaryota.
DR InParanoid; Q5ZKF4; -.
DR OrthoDB; 1458939at2759; -.
DR PhylomeDB; Q5ZKF4; -.
DR PRO; PR:Q5ZKF4; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR Gene3D; 1.10.30.10; -; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; SSF47095; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..348
FT /note="High mobility group protein 20A"
FT /id="PRO_0000238651"
FT DNA_BIND 104..172
FT /note="HMG box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT REGION 1..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 230..274
FT /evidence="ECO:0000255"
FT COMPBIAS 27..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 348 AA; 40121 MW; 3CDD768783F5151C CRC64;
MENLVAGSTL PPLFADEDGS KEGSDVTVTG LAHSESSFTG GTSQPVNNPD LVEDLSQVQQ
LQNESTNTAE NTEQKPEEEQ QRTKRGGWAK GRKRKKPLRD SNAPKSPLTG YVRFMNERRE
QLRAKRPEVP FPEITRMLGN EWSKLPPEEK RRYLDEADRD KERYMRELEQ YQKTEAYKVF
SRKAQDRQKG KLHRQDGARQ PVHDHEKEAD TKERSVFDIP IFTEEFLNHS KAREAELRQL
RKSNMEFEER NAALQKHVES MRTAVEKLEV DVIQERSRNT VLQQHLETLR QALTTSFAGV
PLPGSGETPT METIDSYMNR LHGIIMANPQ ENENLIATVR DVVNRLER