ID   HM20A_XENLA             Reviewed;         345 AA.
AC   Q6AZF8;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=High mobility group protein 20A;
DE   AltName: Full=HMG box-containing protein 20A;
GN   Name=hmg20a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in neuronal differentiation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
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DR   EMBL; BC078062; AAH78062.1; -; mRNA.
DR   RefSeq; NP_001087141.1; NM_001093672.1.
DR   AlphaFoldDB; Q6AZF8; -.
DR   SMR; Q6AZF8; -.
DR   BioGRID; 103890; 1.
DR   MaxQB; Q6AZF8; -.
DR   PRIDE; Q6AZF8; -.
DR   DNASU; 447030; -.
DR   GeneID; 447030; -.
DR   KEGG; xla:447030; -.
DR   CTD; 447030; -.
DR   Xenbase; XB-GENE-955359; hmg20a.L.
DR   OMA; IFTHEFL; -.
DR   OrthoDB; 1458939at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 447030; Expressed in lung and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.30.10; -; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; SSF47095; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..345
FT                   /note="High mobility group protein 20A"
FT                   /id="PRO_0000238652"
FT   DNA_BIND        101..169
FT                   /note="HMG box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT   REGION          1..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          166..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          227..285
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..44
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..127
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   345 AA;  39615 MW;  3689716F337E1E93 CRC64;
     MESTASAVPP SSEDLVADTK ENNQPPFCGT TVSGSSQAPL HPHSPTLQQD EREELTLHQS
     GEQQLGNSGE LRQEEELPKA RRGGWNKGRK RKRSPRDNNA PKAPLTGYVR FMNERREQLR
     TERPDVPFPE ITRIVGSEWS KLPAHEKQHY LDEAEKDKER YTKELQKYQN TDAYQTYSRK
     AKSRQKGRQQ RQEGVRGVPS NTEKESILKE RPIFDIPIFT EEFLNHSKAR EAELRQLRKS
     NMEFEERNAA LQKHVESMRS AVQRLEAELS QEHERNSLLQ QHLQSVRQAL THCLQSVPVP
     GTTETPTLET IDLYMSRLQN AVLTHPKESE VIISGVREVL SQLEG