ID   HM20A_XENTR             Reviewed;         345 AA.
AC   Q6DIJ5;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=High mobility group protein 20A;
DE   AltName: Full=HMG box-containing protein 20A;
GN   Name=hmg20a;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in neuronal differentiation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC075543; AAH75543.1; -; mRNA.
DR   RefSeq; NP_001006760.1; NM_001006759.1.
DR   RefSeq; XP_012821857.1; XM_012966403.2.
DR   RefSeq; XP_012821859.1; XM_012966405.2.
DR   RefSeq; XP_012821860.1; XM_012966406.2.
DR   RefSeq; XP_012821861.1; XM_012966407.2.
DR   AlphaFoldDB; Q6DIJ5; -.
DR   SMR; Q6DIJ5; -.
DR   STRING; 8364.ENSXETP00000012795; -.
DR   PaxDb; Q6DIJ5; -.
DR   DNASU; 448440; -.
DR   GeneID; 448440; -.
DR   KEGG; xtr:448440; -.
DR   CTD; 10363; -.
DR   Xenbase; XB-GENE-955353; hmg20a.
DR   eggNOG; KOG0381; Eukaryota.
DR   HOGENOM; CLU_060006_0_0_1; -.
DR   InParanoid; Q6DIJ5; -.
DR   OMA; IFTHEFL; -.
DR   OrthoDB; 1458939at2759; -.
DR   PhylomeDB; Q6DIJ5; -.
DR   TreeFam; TF106440; -.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000015269; Expressed in testis and 13 other tissues.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   Gene3D; 1.10.30.10; -; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; SSF47095; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..345
FT                   /note="High mobility group protein 20A"
FT                   /id="PRO_0000238653"
FT   DNA_BIND        101..169
FT                   /note="HMG box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT   REGION          1..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          167..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          227..290
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        29..70
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..183
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   345 AA;  39713 MW;  630A8F1B7E59C72A CRC64;
     MENTASAAPP SSEDLVVDTK ENAEPPFCGI SLSGSSQAPF HPQSPTLQQD ERDELILQQS
     GEQQLGNSGE LRQEEELPKT RRGGWTKGRK RKRSPRDNNA PKAPLTGYVR FMNERREQLR
     TERPDVPFPE ITRIVGSEWS KLPAHEKQHY LDEAEKDKER YTKELQQYQN TDAYQTYSRK
     AQSRQKGRQQ RQEGVRGVPI NTEKESILKE RPIFDIPIFT EEFLNHSKAR EAELRQLRKS
     NMEFEERNAA LQKHVESMRS AVQRLEAELN QEQERNSLLQ QHLQSVRQAL THCLQSVPIP
     GTTEIPTLET IDLYMSRLQN AVLTHPKESE VIISGVREVL SQLEG