HM31_CAEEL
ID HM31_CAEEL Reviewed; 260 AA.
AC Q22910;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Homeobox protein ceh-31;
GN Name=ceh-31; ORFNames=C33D12.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FO080757; CCD66476.1; -; Genomic_DNA.
DR PIR; T25611; T25611.
DR RefSeq; NP_508525.3; NM_076124.5.
DR AlphaFoldDB; Q22910; -.
DR SMR; Q22910; -.
DR BioGRID; 56123; 10.
DR IntAct; Q22910; 10.
DR STRING; 6239.C33D12.1; -.
DR EPD; Q22910; -.
DR PaxDb; Q22910; -.
DR PRIDE; Q22910; -.
DR EnsemblMetazoa; C33D12.1.1; C33D12.1.1; WBGene00000452.
DR GeneID; 191621; -.
DR KEGG; cel:CELE_C33D12.1; -.
DR UCSC; C33D12.1; c. elegans.
DR CTD; 191621; -.
DR WormBase; C33D12.1; CE42831; WBGene00000452; ceh-31.
DR eggNOG; KOG0488; Eukaryota.
DR GeneTree; ENSGT00940000169370; -.
DR HOGENOM; CLU_102319_0_0_1; -.
DR InParanoid; Q22910; -.
DR OMA; MELAHRM; -.
DR OrthoDB; 1363285at2759; -.
DR PhylomeDB; Q22910; -.
DR SignaLink; Q22910; -.
DR PRO; PR:Q22910; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00000452; Expressed in larva and 3 other tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR000047; HTH_motif.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN 1..260
FT /note="Homeobox protein ceh-31"
FT /id="PRO_0000048997"
FT DNA_BIND 94..153
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 44..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 260 AA; 28795 MW; 1C8416C04B2287C0 CRC64;
MSMLDLRQFL IPAFFLDPTN QLAAQSSSGG AKINLNSSFR ISDLLDPTSH STNEPDPSPT
SINSSESPSS PRIGSPNTER SVNESPTCVG SKKARKARTI FTDKQLQELE NTFEKQKYLS
VQDRMELAHR MGLTDTQVKT WYQNRRTKWK RQASVGMDLL HDAGNMAAVQ QLLRTNPYWA
NYLSQNTSMF GASNNRPVFN SLVVPTSSMI PASNSQNSLL QFLASQNVKD DISSPKESPS
VSPDSVKNAS VSKKESDEDE
