HM7X_CHICK
ID HM7X_CHICK Reviewed; 124 AA.
AC P15142;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1990, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Homeobox protein CHOX-7;
DE Flags: Fragment;
GN Name=CHOX-7;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2473919; DOI=10.1016/0014-5793(89)80760-4;
RA Fainsod A., Gruenbaum Y.;
RT "A chicken homeo box gene with developmentally regulated expression.";
RL FEBS Lett. 250:381-385(1989).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; X16159; CAA34285.1; -; Genomic_DNA.
DR PIR; S05005; S05005.
DR AlphaFoldDB; P15142; -.
DR SMR; P15142; -.
DR STRING; 9031.ENSGALP00000041607; -.
DR VEuPathDB; HostDB:LOC395377; -.
DR eggNOG; KOG0489; Eukaryota.
DR InParanoid; P15142; -.
DR PhylomeDB; P15142; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0051960; P:regulation of nervous system development; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR031251; GBX-1.
DR InterPro; IPR042982; GBX-1/2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR24334; PTHR24334; 1.
DR PANTHER; PTHR24334:SF2; PTHR24334:SF2; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN <1..124
FT /note="Homeobox protein CHOX-7"
FT /id="PRO_0000048884"
FT DNA_BIND 24..83
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 83..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
SQ SEQUENCE 124 AA; 13683 MW; 973E78867E59A6AC CRC64;
GPKGKGKGGP AAEQPPPGSG AGKSRRRRTA FTSEQLLELE KEFHCKKYLS LTERSQIAHA
LKLSEVQVKI WFQNRRAKWK RIKAGNVSNR SGEPVRNPKI VRAHPGARQS LRRAQPAPAD
RAGA