ID   ANXA9_BOVIN             Reviewed;         345 AA.
AC   Q3ZC08;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Annexin A9;
DE   AltName: Full=Annexin-9;
GN   Name=ANXA9;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Heart ventricle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a low affinity receptor for acetylcholine.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the annexin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01245, ECO:0000305}.
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DR   EMBL; BC102991; AAI02992.1; -; mRNA.
DR   RefSeq; NP_001030450.1; NM_001035373.2.
DR   AlphaFoldDB; Q3ZC08; -.
DR   SMR; Q3ZC08; -.
DR   STRING; 9913.ENSBTAP00000020350; -.
DR   PaxDb; Q3ZC08; -.
DR   GeneID; 528055; -.
DR   KEGG; bta:528055; -.
DR   CTD; 8416; -.
DR   eggNOG; KOG0819; Eukaryota.
DR   InParanoid; Q3ZC08; -.
DR   OrthoDB; 856254at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0031982; C:vesicle; IBA:GO_Central.
DR   GO; GO:0005262; F:calcium channel activity; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IBA:GO_Central.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR   GO; GO:0001786; F:phosphatidylserine binding; IBA:GO_Central.
DR   GO; GO:0019834; F:phospholipase A2 inhibitor activity; IBA:GO_Central.
DR   GO; GO:0002020; F:protease binding; IBA:GO_Central.
DR   GO; GO:0046790; F:virion binding; IBA:GO_Central.
DR   Gene3D; 1.10.220.10; -; 4.
DR   InterPro; IPR001464; Annexin.
DR   InterPro; IPR018502; Annexin_repeat.
DR   InterPro; IPR018252; Annexin_repeat_CS.
DR   InterPro; IPR037104; Annexin_sf.
DR   InterPro; IPR009116; ANX9.
DR   PANTHER; PTHR10502:SF122; PTHR10502:SF122; 1.
DR   Pfam; PF00191; Annexin; 4.
DR   PRINTS; PR00196; ANNEXIN.
DR   PRINTS; PR01812; ANNEXINXXXI.
DR   SMART; SM00335; ANX; 3.
DR   SUPFAM; SSF47874; SSF47874; 1.
DR   PROSITE; PS00223; ANNEXIN_1; 1.
DR   PROSITE; PS51897; ANNEXIN_2; 4.
PE   2: Evidence at transcript level;
KW   Annexin; Reference proteome; Repeat.
FT   CHAIN           1..345
FT                   /note="Annexin A9"
FT                   /id="PRO_0000236218"
FT   REPEAT          41..112
FT                   /note="Annexin 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01245"
FT   REPEAT          113..184
FT                   /note="Annexin 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01245"
FT   REPEAT          197..266
FT                   /note="Annexin 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01245"
FT   REPEAT          270..341
FT                   /note="Annexin 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01245"
SQ   SEQUENCE   345 AA;  38293 MW;  59AEC7550C78AA98 CRC64;
     MSVTHGKMGL SLTQEILSHL GLANKTAAWG TLGTLRTFLS FSADKDVQRL LKAIAGQGVD
     RIAILDVLTN RSREQRQLIS RAFHERTQQD LLKSLQAALS GNLERIVVAL LQPAAHLDAR
     ELRTALKGSG SAEDVALEIL ATRTPPQLQE CLAVYKHNFQ VDAAEDIKSE TRGILRDLLL
     ALAKGGREAY TGIIDYNLAA QDVQALKQAE GPSTERTWVL VFTQRNPEHL VRVLNQYQWY
     TGHGLEKTVR ARFHGAACVA LLNLASVIRN TPLYFADKLH QALQETEPNY QALMRILISR
     SETDLLSIRA EFRKKFGKSL YSSLQDAVKG DCRSALLALC RAEDL