HMDY_METJA
ID HMDY_METJA Reviewed; 353 AA.
AC Q58734;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338;
GN OrderedLocusNames=MJ1338;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
CC -!- SIMILARITY: Belongs to the HMD family. {ECO:0000305}.
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DR EMBL; L77117; AAB99348.1; -; Genomic_DNA.
DR PIR; A64467; A64467.
DR PDB; 4YT2; X-ray; 1.65 A; A/B=8-353.
DR PDB; 4YT4; X-ray; 2.20 A; A=1-353.
DR PDB; 4YT5; X-ray; 1.90 A; A/B=1-353.
DR PDB; 4YT8; X-ray; 1.90 A; A/B=1-353.
DR PDB; 6HUX; X-ray; 2.50 A; A=1-353.
DR PDBsum; 4YT2; -.
DR PDBsum; 4YT4; -.
DR PDBsum; 4YT5; -.
DR PDBsum; 4YT8; -.
DR PDBsum; 6HUX; -.
DR AlphaFoldDB; Q58734; -.
DR SMR; Q58734; -.
DR STRING; 243232.MJ_1338; -.
DR EnsemblBacteria; AAB99348; AAB99348; MJ_1338.
DR KEGG; mja:MJ_1338; -.
DR eggNOG; arCOG03195; Archaea.
DR HOGENOM; CLU_069755_0_0_2; -.
DR OMA; IMTLQTM; -.
DR PhylomeDB; Q58734; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.1300; -; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR004889; HMD_C.
DR InterPro; IPR038182; HMD_C_sf.
DR InterPro; IPR010063; HMDII/III.
DR InterPro; IPR024190; METHMP_Hmd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR Pfam; PF03201; HMD; 1.
DR PIRSF; PIRSF016158; HMD; 1.
DR PIRSF; PIRSF500166; HMDII_III; 1.
DR SUPFAM; SSF48179; SSF48179; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
DR TIGRFAMs; TIGR01724; hmd_rel; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Oxidoreductase; Reference proteome.
FT CHAIN 1..353
FT /note="H(2)-forming methylenetetrahydromethanopterin
FT dehydrogenase-related protein MJ1338"
FT /id="PRO_0000218518"
FT HELIX 4..10
FT /evidence="ECO:0007829|PDB:6HUX"
FT STRAND 13..17
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 22..26
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 31..34
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 43..52
FT /evidence="ECO:0007829|PDB:4YT2"
FT STRAND 56..60
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 64..66
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 69..77
FT /evidence="ECO:0007829|PDB:4YT2"
FT STRAND 81..84
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 86..92
FT /evidence="ECO:0007829|PDB:4YT2"
FT STRAND 94..98
FT /evidence="ECO:0007829|PDB:4YT2"
FT TURN 102..104
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 105..114
FT /evidence="ECO:0007829|PDB:4YT2"
FT STRAND 122..125
FT /evidence="ECO:0007829|PDB:4YT2"
FT STRAND 127..129
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 131..142
FT /evidence="ECO:0007829|PDB:4YT2"
FT TURN 143..148
FT /evidence="ECO:0007829|PDB:4YT2"
FT STRAND 150..153
FT /evidence="ECO:0007829|PDB:4YT2"
FT STRAND 167..173
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 183..195
FT /evidence="ECO:0007829|PDB:4YT2"
FT STRAND 199..204
FT /evidence="ECO:0007829|PDB:4YT2"
FT TURN 205..207
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 208..212
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 216..235
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 241..271
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 273..281
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 290..300
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 304..312
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 323..334
FT /evidence="ECO:0007829|PDB:4YT2"
FT HELIX 336..351
FT /evidence="ECO:0007829|PDB:4YT2"
SQ SEQUENCE 353 AA; 38212 MW; 2AFF9FD87675F6A6 CRC64;
MRNIRKIKVD NMKVSVYGAG NQNLYINKLN LPEKFGGEPP YGGSRMAIEF AEAGHDVVLA
EPNKNIMSDD LWKKVEDAGV KVVSDDVEAA KHGEIHVLFT PFGKATFRIA KTIIEHVPEN
AVICNTCTVS PVVLYYSLEP ILRTKRKDVG ISSMHPAAVP GTPQHGHYVI GGKTTDGKEL
ATEEQIKKAV ELAKSAGKEA YVVPADVSSV VADMGSLVTA VALSGVLDYY TVGRKIINAP
KKMIEQQVIM TLQTMASLVE TSGIEGMVKA LNPELLIRSA SSMKLLDRQK DLDAALEILQ
NLDETLKAEV EKAEIKPTTL VAAQSLVKEI KTLIGGAAAE GAIKRSARKL FEH
