HMG14_ARATH
ID HMG14_ARATH Reviewed; 151 AA.
AC O64702; Q2V430;
DT 02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=High mobility group B protein 14;
DE AltName: Full=Nucleosome/chromatin assembly factor group D 14;
GN Name=HMGB14; Synonyms=NFD14; OrderedLocusNames=At2g34450;
GN ORFNames=F13P17.25;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=O64702-1; Sequence=Displayed;
CC Name=2;
CC IsoId=O64702-2; Sequence=VSP_039946;
CC -!- SIMILARITY: Belongs to the HMGB family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC004077; AAC26692.2; -; Genomic_DNA.
DR EMBL; AC004481; AAM14948.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08975.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08976.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62822.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62823.1; -; Genomic_DNA.
DR EMBL; AK118955; BAC43535.1; -; mRNA.
DR EMBL; BT005660; AAO64080.1; -; mRNA.
DR EMBL; AY084626; AAM61189.1; -; mRNA.
DR PIR; T02332; T02332.
DR RefSeq; NP_001031480.1; NM_001036403.1. [O64702-2]
DR RefSeq; NP_001318353.1; NM_001336514.1. [O64702-1]
DR RefSeq; NP_001324951.1; NM_001336515.1. [O64702-1]
DR RefSeq; NP_565788.1; NM_128997.3. [O64702-1]
DR AlphaFoldDB; O64702; -.
DR SMR; O64702; -.
DR BioGRID; 3355; 14.
DR IntAct; O64702; 9.
DR STRING; 3702.AT2G34450.2; -.
DR PaxDb; O64702; -.
DR PRIDE; O64702; -.
DR ProteomicsDB; 230259; -. [O64702-1]
DR EnsemblPlants; AT2G34450.1; AT2G34450.1; AT2G34450. [O64702-1]
DR EnsemblPlants; AT2G34450.2; AT2G34450.2; AT2G34450. [O64702-2]
DR EnsemblPlants; AT2G34450.3; AT2G34450.3; AT2G34450. [O64702-1]
DR EnsemblPlants; AT2G34450.4; AT2G34450.4; AT2G34450. [O64702-1]
DR GeneID; 818008; -.
DR Gramene; AT2G34450.1; AT2G34450.1; AT2G34450. [O64702-1]
DR Gramene; AT2G34450.2; AT2G34450.2; AT2G34450. [O64702-2]
DR Gramene; AT2G34450.3; AT2G34450.3; AT2G34450. [O64702-1]
DR Gramene; AT2G34450.4; AT2G34450.4; AT2G34450. [O64702-1]
DR KEGG; ath:AT2G34450; -.
DR Araport; AT2G34450; -.
DR TAIR; locus:2040834; AT2G34450.
DR eggNOG; KOG0381; Eukaryota.
DR InParanoid; O64702; -.
DR OMA; FDAMKPK; -.
DR PhylomeDB; O64702; -.
DR PRO; PR:O64702; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O64702; baseline and differential.
DR Genevisible; O64702; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR Gene3D; 1.10.30.10; -; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; SSF47095; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Nucleus; Phosphoprotein;
KW Reference proteome.
FT CHAIN 1..151
FT /note="High mobility group B protein 14"
FT /id="PRO_0000399939"
FT DNA_BIND 63..132
FT /note="HMG box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..60
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 150
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:O49595"
FT VAR_SEQ 93
FT /note="E -> EV (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_039946"
SQ SEQUENCE 151 AA; 17499 MW; 1BDCB99C1ED68327 CRC64;
MTKRAPKSGP LSPSCSGGSS RNLELAVKSS EGARRSTRLR LQPLRKPKTS PKKKPVKLQT
KMPKKPATAF FFFLDDFRKQ YQEENPDVKS MREIGKTCGE KWKTMTYEEK VKYYDIATEK
REEFHRAMTE YTKRMESGAH DESETDSDYS E
