HMG15_ARATH
ID HMG15_ARATH Reviewed; 448 AA.
AC Q9MAT6;
DT 02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=High mobility group B protein 15;
DE AltName: Full=Nucleosome/chromatin assembly factor group D 15;
GN Name=HMGB15; Synonyms=NFD15; OrderedLocusNames=At1g04880;
GN ORFNames=F13M7.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Binds preferentially DNA with A/T-rich content.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267,
CC ECO:0000255|PROSITE-ProRule:PRU00355}.
CC -!- SIMILARITY: Belongs to the HMGB family. {ECO:0000305}.
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DR EMBL; AC004809; AAF40449.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27755.1; -; Genomic_DNA.
DR EMBL; BT020255; AAV84476.1; -; mRNA.
DR EMBL; BT020442; AAW30021.1; -; mRNA.
DR EMBL; AB493433; BAH30271.1; -; mRNA.
DR PIR; B86182; B86182.
DR RefSeq; NP_171980.1; NM_100366.4.
DR AlphaFoldDB; Q9MAT6; -.
DR SMR; Q9MAT6; -.
DR BioGRID; 24623; 6.
DR IntAct; Q9MAT6; 3.
DR STRING; 3702.AT1G04880.1; -.
DR iPTMnet; Q9MAT6; -.
DR PaxDb; Q9MAT6; -.
DR PRIDE; Q9MAT6; -.
DR ProteomicsDB; 230354; -.
DR EnsemblPlants; AT1G04880.1; AT1G04880.1; AT1G04880.
DR GeneID; 839388; -.
DR Gramene; AT1G04880.1; AT1G04880.1; AT1G04880.
DR KEGG; ath:AT1G04880; -.
DR Araport; AT1G04880; -.
DR TAIR; locus:2010587; AT1G04880.
DR eggNOG; KOG0381; Eukaryota.
DR eggNOG; KOG2744; Eukaryota.
DR HOGENOM; CLU_035371_1_0_1; -.
DR InParanoid; Q9MAT6; -.
DR OMA; PMATYEE; -.
DR OrthoDB; 891562at2759; -.
DR PhylomeDB; Q9MAT6; -.
DR PRO; PR:Q9MAT6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9MAT6; baseline and differential.
DR Genevisible; Q9MAT6; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0090406; C:pollen tube; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000400; F:four-way junction DNA binding; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0019760; P:glucosinolate metabolic process; IMP:TAIR.
DR GO; GO:0009846; P:pollen germination; IMP:TAIR.
DR GO; GO:0009860; P:pollen tube growth; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR CDD; cd16872; ARID_HMGB9-like; 1.
DR Gene3D; 1.10.150.60; -; 1.
DR Gene3D; 1.10.30.10; -; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR045303; ARID_HMGB9-like.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF46774; SSF46774; 1.
DR SUPFAM; SSF47095; SSF47095; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..448
FT /note="High mobility group B protein 15"
FT /id="PRO_0000399940"
FT DOMAIN 29..120
FT /note="ARID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00355"
FT DNA_BIND 263..330
FT /note="HMG box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT REGION 219..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 50004 MW; 246DE27651D59CD3 CRC64;
MASSSCLKQG SVPMNNVCVT PEATYEAVVA DPRLFMTSLE RLHSLLGTKF MVPIIGGRDL
DLHKLFVEVT SRGGINKILN ERRWKEVTAT FVFPPTATNA SYVLRKYYFS LLNNYEQIYF
FRSNGQIPPD SMQSPSARPC FIQGAIRPSQ ELQALTFTPQ PKINTAEFLG GSLAGSNVVG
VIDGKFESGY LVTVTIGSEQ LKGVLYQLLP QNTVSYQTPQ QSHGVLPNTL NISANPQGVA
GGVTKRRRRR KKSEIKRRDP DHPKPNRSGY NFFFAEQHAR LKPLHPGKDR DISRMIGELW
NKLNEDEKLI YQGKAMEDKE RYRTEMEDYR EKKKNGQLIS NAVPLQQRLP EQNVDMAEAD
LPIDEVEEDD EEGDSSGSSG ESEPHDDQSI ETDPELEEPS LNPSGPNLNP NPTEIVVAPK
EKNGDVVMET SPLKKADEPT VAVTAEQN
