HMG1B_CHITE
ID HMG1B_CHITE Reviewed; 110 AA.
AC P40623;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Mobility group protein 1B;
GN Name=HMG1B;
OS Chironomus tentans (Midge) (Camptochironomus tentans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC Chironominae; Chironomus.
OX NCBI_TaxID=7153;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Embryonic epithelium;
RX PubMed=1512255; DOI=10.1016/s0021-9258(18)41909-6;
RA Wisniewski J.R., Schulze E.;
RT "Insect proteins homologous to mammalian high mobility group protein 1.
RT Characterization and DNA-binding properties.";
RL J. Biol. Chem. 267:17170-17177(1992).
CC -!- FUNCTION: Found in condensed chromomeres. Binds preferentially to AT-
CC rich DNA.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- SIMILARITY: Belongs to the HMGB family. {ECO:0000305}.
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DR EMBL; M93254; AAA21713.1; -; mRNA.
DR PIR; B43436; B43436.
DR AlphaFoldDB; P40623; -.
DR SMR; P40623; -.
DR PRIDE; P40623; -.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.30.10; -; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; SSF47095; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 3: Inferred from homology;
KW Chromosome; DNA-binding; Nucleus.
FT CHAIN 1..110
FT /note="Mobility group protein 1B"
FT /id="PRO_0000048551"
FT DNA_BIND 5..71
FT /note="HMG box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT REGION 71..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 110 AA; 12150 MW; B3491735713333C4 CRC64;
MADKPKRPLS AYMLWLNSAR ESIKRENPDF KVTEVAKKGG ELWRGLKDKS EWEAKAATAK
QNYIRALQEY ERNGGGGDDK GKKRKGAAPK KGAGKKSKKG AHSDDDGDSE