ID   HMGN1_CHICK             Reviewed;         103 AA.
AC   P12274;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Non-histone chromosomal protein HMG-14B;
GN   Name=HMG14;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3417670; DOI=10.1016/s0021-9258(18)68268-7;
RA   Srikantha T., Landsman D., Bustin M.;
RT   "Cloning of the chicken chromosomal protein HMG-14 cDNA reveals a unique
RT   protein with a conserved DNA binding domain.";
RL   J. Biol. Chem. 263:13500-13503(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2153836; DOI=10.1016/0022-2836(90)90010-j;
RA   Srikantha T., Landsman D., Bustin M.;
RT   "A single copy gene for chicken chromosomal protein HMG-14b has
RT   evolutionarily conserved features, has lost one of its introns and codes
RT   for a rapidly evolving protein.";
RL   J. Mol. Biol. 211:49-61(1990).
CC   -!- FUNCTION: Binds to the inner side of the nucleosomal DNA thus altering
CC       the interaction between the DNA and the histone octamer. May be
CC       involved in the process which maintains transcribable genes in a unique
CC       chromatin conformation.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- MISCELLANEOUS: There are two HMG-14 proteins in chicken: HMG-14A the
CC       major component, and HMG-14B the minor component.
CC   -!- SIMILARITY: Belongs to the HMGN family. {ECO:0000305}.
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DR   EMBL; M20817; AAB59965.1; -; mRNA.
DR   EMBL; X52707; CAA36932.1; -; Genomic_DNA.
DR   EMBL; X52708; CAA36932.1; JOINED; Genomic_DNA.
DR   PIR; S08180; S08180.
DR   AlphaFoldDB; P12274; -.
DR   VEuPathDB; HostDB:geneid_395999; -.
DR   eggNOG; ENOG502S7UM; Eukaryota.
DR   InParanoid; P12274; -.
DR   PhylomeDB; P12274; -.
DR   PRO; PR:P12274; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0000785; C:chromatin; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; IBA:GO_Central.
DR   InterPro; IPR000079; HMGN_fam.
DR   Pfam; PF01101; HMG14_17; 1.
DR   PRINTS; PR00925; NONHISHMG17.
DR   SMART; SM00527; HMG17; 1.
DR   PROSITE; PS00355; HMG14_17; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT   CHAIN           2..103
FT                   /note="Non-histone chromosomal protein HMG-14B"
FT                   /id="PRO_0000206693"
FT   REGION          1..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..69
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..103
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   103 AA;  11180 MW;  86E532DF9774D969 CRC64;
     MPKRKVAASR GGREEVPKRR SARLSAKPVP DKAEPKAKAL AAKDKSENKK AQSKGKKGPK
     GKQTEETNQE QIKDNLPAEN GETKSEETPA SDAAVEKEEV KSE