ID   HMGN2_PONAB             Reviewed;          90 AA.
AC   Q5RAA0;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Non-histone chromosomal protein HMG-17;
DE   AltName: Full=High mobility group nucleosome-binding domain-containing protein 2;
GN   Name=HMGN2; Synonyms=HMG17;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds to the inner side of the nucleosomal DNA thus altering
CC       the interaction between the DNA and the histone octamer. May be
CC       involved in the process which maintains transcribable genes in a unique
CC       chromatin conformation (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Cytoplasmic enrichment upon phosphorylation. {ECO:0000250}.
CC   -!- PTM: Phosphorylation favors cytoplasmic localization. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HMGN family. {ECO:0000305}.
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DR   EMBL; CR859118; CAH91310.1; -; mRNA.
DR   RefSeq; NP_001125775.1; NM_001132303.1.
DR   AlphaFoldDB; Q5RAA0; -.
DR   STRING; 9601.ENSPPYP00000001943; -.
DR   GeneID; 100172702; -.
DR   KEGG; pon:100172702; -.
DR   CTD; 3151; -.
DR   eggNOG; ENOG502S5FK; Eukaryota.
DR   InParanoid; Q5RAA0; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0000785; C:chromatin; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IEA:InterPro.
DR   InterPro; IPR000079; HMGN_fam.
DR   Pfam; PF01101; HMG14_17; 1.
DR   PRINTS; PR00925; NONHISHMG17.
DR   SMART; SM00527; HMG17; 1.
DR   PROSITE; PS00355; HMG14_17; 1.
PE   3: Inferred from homology;
KW   Acetylation; ADP-ribosylation; Cytoplasm; DNA-binding; Isopeptide bond;
KW   Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation.
FT   CHAIN           1..90
FT                   /note="Non-histone chromosomal protein HMG-17"
FT                   /id="PRO_0000206700"
FT   REGION          1..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        54..90
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         25
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P05204"
FT   MOD_RES         29
FT                   /note="ADP-ribosylserine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P05204"
FT   MOD_RES         29
FT                   /note="Phosphoserine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P05204"
FT   MOD_RES         82
FT                   /note="N6-acetyllysine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P05204"
FT   CROSSLNK        82
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2); alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P05204"
SQ   SEQUENCE   90 AA;  9451 MW;  B1C58E51103722C8 CRC64;
     MPKRKAEGDA KGDKAKVKDE PQRRSARLSA KPAPPKPEPK PKKAPAKKGE KVPKGKKGKA
     DADKEGNNPA ENGDAKTDQA QKAEGAGDAK