ID   HMUS_YERPE              Reviewed;         345 AA.
AC   Q56990; Q0WK24;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   25-MAY-2022, entry version 119.
DE   RecName: Full=Hemin transport protein HmuS;
GN   Name=hmuS; OrderedLocusNames=YPO0282, y0542, YP_0437;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM6;
RX   PubMed=9026634; DOI=10.1111/j.1365-2958.1996.tb02512.x;
RA   Hornung J.M., Jones H.A., Perry R.D.;
RT   "The hmu locus of Yersinia pestis is essential for utilization of free
RT   haemin and haem-protein complexes as iron sources.";
RL   Mol. Microbiol. 20:725-739(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       hemin.
CC   -!- SIMILARITY: To Y.enterocolitica HemS. {ECO:0000305}.
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DR   EMBL; U60647; AAC64867.1; -; Genomic_DNA.
DR   EMBL; AL590842; CAL18968.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM84130.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS60708.1; -; Genomic_DNA.
DR   PIR; AF0035; AF0035.
DR   PIR; T12070; T12070.
DR   RefSeq; WP_002209061.1; NZ_WUCM01000046.1.
DR   RefSeq; YP_002345364.1; NC_003143.1.
DR   AlphaFoldDB; Q56990; -.
DR   SMR; Q56990; -.
DR   IntAct; Q56990; 1.
DR   STRING; 214092.YPO0282; -.
DR   PaxDb; Q56990; -.
DR   EnsemblBacteria; AAM84130; AAM84130; y0542.
DR   EnsemblBacteria; AAS60708; AAS60708; YP_0437.
DR   GeneID; 66843244; -.
DR   KEGG; ype:YPO0282; -.
DR   KEGG; ypk:y0542; -.
DR   KEGG; ypm:YP_0437; -.
DR   PATRIC; fig|214092.21.peg.515; -.
DR   eggNOG; COG3720; Bacteria.
DR   HOGENOM; CLU_034543_0_0_6; -.
DR   OMA; DTHEFFG; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR   InterPro; IPR007845; HemS/ChuX_dom.
DR   Pfam; PF05171; HemS; 2.
PE   4: Predicted;
KW   Ion transport; Iron; Iron transport; Reference proteome; Transport.
FT   CHAIN           1..345
FT                   /note="Hemin transport protein HmuS"
FT                   /id="PRO_0000084010"
SQ   SEQUENCE   345 AA;  39091 MW;  E5CE97FDC3FED107 CRC64;
     MNASLYQQYV QAKAEHPGKY ARDLATLMGI SEAELTHSRV GHDAKRLQSD ARALLAALES
     VGEVKAITRN TYAVHEQVGR YENQHLNGHA GLILNPRALD LRLFLNQWAS AFTLTEETRH
     GVRHSIQFFD HQGDALHKVY VTEQTDMSAW EALLAQFIIP ENPALQLEPL STPEAVEPTA
     DDATVDSEWR AMTDVHQFFQ LLKRNNLTRQ QAFRAVGDDL AYQVDNNSLT QLLHIAQQDQ
     NEIMIFVGNR GCVQIFTGLI EKVTPHNEWI NVFNQRFTLH LIETAIAESW ITRKPTKDGF
     VTSLELFAAD GTQLAQLYGQ RTEGQPEQNQ WREQIARLIN KDIAA