ID   HMUV_DEIRA              Reviewed;         261 AA.
AC   Q9RZU5;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Hemin import ATP-binding protein HmuV {ECO:0000255|HAMAP-Rule:MF_01718};
DE            EC=7.6.2.- {ECO:0000255|HAMAP-Rule:MF_01718};
GN   Name=hmuV {ECO:0000255|HAMAP-Rule:MF_01718}; OrderedLocusNames=DR_B0016;
OS   Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS   4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OG   Plasmid megaplasmid MP1.
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=243230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA   White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA   Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA   Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA   Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA   Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA   Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA   Fraser C.M.;
RT   "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT   R1.";
RL   Science 286:1571-1577(1999).
CC   -!- FUNCTION: Part of the ABC transporter complex HmuTUV involved in hemin
CC       import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HmuV),
CC       two transmembrane proteins (HmuU) and a solute-binding protein (HmuT).
CC       {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01718};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Heme (hemin)
CC       importer (TC 3.A.1.14.5) family. {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE001826; AAF12577.1; -; Genomic_DNA.
DR   PIR; H75619; H75619.
DR   RefSeq; NP_051559.1; NC_000958.1.
DR   RefSeq; WP_010883994.1; NZ_CP015083.1.
DR   AlphaFoldDB; Q9RZU5; -.
DR   SMR; Q9RZU5; -.
DR   EnsemblBacteria; AAF12577; AAF12577; DR_B0016.
DR   KEGG; dra:DR_B0016; -.
DR   PATRIC; fig|243230.17.peg.14; -.
DR   HOGENOM; CLU_000604_1_11_0; -.
DR   InParanoid; Q9RZU5; -.
DR   OMA; KALCQEI; -.
DR   OrthoDB; 1752365at2; -.
DR   Proteomes; UP000002524; Plasmid megaplasmid MP1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51261; HMUV; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Plasmid;
KW   Reference proteome; Translocase; Transport.
FT   CHAIN           1..261
FT                   /note="Hemin import ATP-binding protein HmuV"
FT                   /id="PRO_0000269588"
FT   DOMAIN          8..243
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
FT   BINDING         40..47
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
SQ   SEQUENCE   261 AA;  28142 MW;  9A21D9951A3D91C3 CRC64;
     MTASSPSIRV TDLSYSVAGR ELLSKLKFHL QSGEMLAVLG RNGAGKSTLL KHLTGELGKS
     GVELFGQPLR DIKPAEAAKR RAVLPQQTPL SFAYEVLDVV LLGRIPHGQR ETVQDRAIAA
     ACLERVGLSG YETRDVLTLS GGEQQRVHFA RTLAQLHGVI GERVLLLDEP TASLDLAHQH
     ATLRLARELC REGVGVLAVL HDLNLAAQYA DRVLMLAEGH VIACDHPAVA LTPESIRTAY
     GHEVLVTQHP CLNCPLIVSA S