AOC1_ARATH
ID AOC1_ARATH Reviewed; 254 AA.
AC Q9LS03; Q94IH9;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Allene oxide cyclase 1, chloroplastic;
DE EC=5.3.99.6;
DE AltName: Full=Early-responsive to dehydration 12 protein;
DE Flags: Precursor;
GN Name=AOC1; Synonyms=ERD12; OrderedLocusNames=At3g25760;
GN ORFNames=K13N2.10, K13N2_8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, SUBCELLULAR LOCATION, AND
RP INDUCTION.
RC STRAIN=cv. Columbia; TISSUE=Leaf;
RX PubMed=12777050; DOI=10.1023/a:1023049319723;
RA Stenzel I., Hause B., Miersch O., Kurz T., Maucher H., Weichart H.,
RA Ziegler J., Feussner I., Wasternack C.;
RT "Jasmonate biosynthesis and the allene oxide cyclase family of Arabidopsis
RT thaliana.";
RL Plant Mol. Biol. 51:895-911(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 3-254.
RX PubMed=8075396; DOI=10.1007/bf00028874;
RA Kiyosue T., Yamaguchi-shinozaki K., Shinozaki K.;
RT "Cloning of cDNAs for genes that are early-responsive to dehydration stress
RT (ERDs) in Arabidopsis thaliana L.: identification of three ERDs as HSP
RT cognate genes.";
RL Plant Mol. Biol. 25:791-798(1994).
RN [6]
RP X-RAY CRYSTALLOGRAPHY (1.79 ANGSTROMS) OF 67-254.
RA Wesenberg G.E., Phillips G.N. Jr., Han B.W., Bitto E., Bingman C.A.,
RA Allard S.T.M.;
RT "X-ray structure of allene oxide cyclase from Arabidopsis thaliana gene
RT At3g25760.";
RL Submitted (JUN-2005) to the PDB data bank.
CC -!- FUNCTION: Involved in the production of 12-oxo-phytodienoic acid
CC (OPDA), a precursor of jasmonic acid.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate =
CC (10Z,15Z)-12-oxophytodienoate; Xref=Rhea:RHEA:22592,
CC ChEBI:CHEBI:36438, ChEBI:CHEBI:57411; EC=5.3.99.6;
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:12777050}.
CC -!- TISSUE SPECIFICITY: Highly expressed in fully developed leaves.
CC {ECO:0000269|PubMed:12777050}.
CC -!- INDUCTION: By dehydration stress. High local and systemic induction by
CC wounding. {ECO:0000269|PubMed:12777050}.
CC -!- MISCELLANEOUS: The four allene oxide cyclase proteins (AOC1, AOC2, AOC3
CC and AOC4) are encoded by duplicated genes. They are very similar, and
CC most experiments involving antibodies do not discriminate between the
CC different members.
CC -!- SIMILARITY: Belongs to the allene oxide cyclase family. {ECO:0000305}.
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DR EMBL; AJ308483; CAC83761.1; -; mRNA.
DR EMBL; AB028607; BAA95763.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77065.1; -; Genomic_DNA.
DR EMBL; AK175392; BAD43155.1; -; mRNA.
DR EMBL; AK176777; BAD44540.1; -; mRNA.
DR EMBL; AB039931; BAB63918.1; -; mRNA.
DR RefSeq; NP_189204.1; NM_113475.5.
DR PDB; 1ZVC; X-ray; 1.79 A; A=67-254.
DR PDBsum; 1ZVC; -.
DR AlphaFoldDB; Q9LS03; -.
DR SMR; Q9LS03; -.
DR STRING; 3702.AT3G25760.1; -.
DR PaxDb; Q9LS03; -.
DR PRIDE; Q9LS03; -.
DR ProteomicsDB; 244959; -.
DR DNASU; 822167; -.
DR EnsemblPlants; AT3G25760.1; AT3G25760.1; AT3G25760.
DR GeneID; 822167; -.
DR Gramene; AT3G25760.1; AT3G25760.1; AT3G25760.
DR KEGG; ath:AT3G25760; -.
DR Araport; AT3G25760; -.
DR TAIR; locus:2085999; AT3G25760.
DR eggNOG; ENOG502QPP8; Eukaryota.
DR HOGENOM; CLU_069000_0_0_1; -.
DR InParanoid; Q9LS03; -.
DR OMA; KACEPQA; -.
DR OrthoDB; 1284108at2759; -.
DR PhylomeDB; Q9LS03; -.
DR BioCyc; ARA:AT3G25760-MON; -.
DR BRENDA; 5.3.99.6; 399.
DR EvolutionaryTrace; Q9LS03; -.
DR PRO; PR:Q9LS03; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LS03; baseline and differential.
DR Genevisible; Q9LS03; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; HDA:TAIR.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0046423; F:allene-oxide cyclase activity; ISS:TAIR.
DR GO; GO:0009695; P:jasmonic acid biosynthetic process; TAS:TAIR.
DR Gene3D; 2.40.480.10; -; 1.
DR InterPro; IPR009410; Allene_ox_cyc.
DR InterPro; IPR044859; Allene_oxi_cyc_Dirigent.
DR InterPro; IPR034871; Allene_oxi_cyc_sf.
DR PANTHER; PTHR31843; PTHR31843; 1.
DR Pfam; PF06351; Allene_ox_cyc; 1.
DR SUPFAM; SSF141493; SSF141493; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Chloroplast; Isomerase; Plastid; Reference proteome;
KW Stress response; Transit peptide.
FT TRANSIT 1..78
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 79..254
FT /note="Allene oxide cyclase 1, chloroplastic"
FT /id="PRO_0000001702"
FT REGION 44..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 83..90
FT /evidence="ECO:0007829|PDB:1ZVC"
FT STRAND 114..117
FT /evidence="ECO:0007829|PDB:1ZVC"
FT STRAND 120..123
FT /evidence="ECO:0007829|PDB:1ZVC"
FT STRAND 129..143
FT /evidence="ECO:0007829|PDB:1ZVC"
FT TURN 144..147
FT /evidence="ECO:0007829|PDB:1ZVC"
FT STRAND 148..158
FT /evidence="ECO:0007829|PDB:1ZVC"
FT HELIX 160..162
FT /evidence="ECO:0007829|PDB:1ZVC"
FT STRAND 163..172
FT /evidence="ECO:0007829|PDB:1ZVC"
FT STRAND 177..186
FT /evidence="ECO:0007829|PDB:1ZVC"
FT TURN 187..190
FT /evidence="ECO:0007829|PDB:1ZVC"
FT STRAND 192..201
FT /evidence="ECO:0007829|PDB:1ZVC"
FT TURN 202..204
FT /evidence="ECO:0007829|PDB:1ZVC"
FT STRAND 205..213
FT /evidence="ECO:0007829|PDB:1ZVC"
FT HELIX 221..223
FT /evidence="ECO:0007829|PDB:1ZVC"
FT HELIX 238..242
FT /evidence="ECO:0007829|PDB:1ZVC"
FT HELIX 245..247
FT /evidence="ECO:0007829|PDB:1ZVC"
SQ SEQUENCE 254 AA; 27802 MW; 7CBBDCCD10EFE410 CRC64;
MASSTISLQS ISMTTLNNLS YSKQFHRSSL LGFSKSFQNF GISSNGPGSS SPTSFTPKKK
LTPTRALSQN LGNTENPRPS KVQELSVYEI NDLDRHSPKI LKNAFSFRFG LGDLVPFTNK
LYTGDLKKRV GITAGLCVVI EHVPEKNGDR FEATYSFYFG DYGHLSVQGP YLTYEDSFLA
ITGGAGIFEG AYGQVKLQQL VYPTKLFYTF YLKGLANDLP LELIGTPVPP SKDVEPAPEA
KALKPSGVVS NFTN
