HMUV_GLOVI
ID HMUV_GLOVI Reviewed; 275 AA.
AC Q7NN36;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Hemin import ATP-binding protein HmuV {ECO:0000255|HAMAP-Rule:MF_01718};
DE EC=7.6.2.- {ECO:0000255|HAMAP-Rule:MF_01718};
GN Name=hmuV {ECO:0000255|HAMAP-Rule:MF_01718}; OrderedLocusNames=gll0578;
OS Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC Bacteria; Cyanobacteria; Gloeobacteria; Gloeobacterales; Gloeobacteraceae;
OC Gloeobacter.
OX NCBI_TaxID=251221;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29082 / PCC 7421;
RX PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA Tabata S.;
RT "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT cyanobacterium that lacks thylakoids.";
RL DNA Res. 10:137-145(2003).
CC -!- FUNCTION: Part of the ABC transporter complex HmuTUV involved in hemin
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01718}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HmuV),
CC two transmembrane proteins (HmuU) and a solute-binding protein (HmuT).
CC {ECO:0000255|HAMAP-Rule:MF_01718}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01718}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01718}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Heme (hemin)
CC importer (TC 3.A.1.14.5) family. {ECO:0000255|HAMAP-Rule:MF_01718}.
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DR EMBL; BA000045; BAC88519.1; -; Genomic_DNA.
DR RefSeq; NP_923524.1; NC_005125.1.
DR RefSeq; WP_011140581.1; NC_005125.1.
DR AlphaFoldDB; Q7NN36; -.
DR SMR; Q7NN36; -.
DR STRING; 251221.35211140; -.
DR EnsemblBacteria; BAC88519; BAC88519; BAC88519.
DR KEGG; gvi:gll0578; -.
DR PATRIC; fig|251221.4.peg.586; -.
DR eggNOG; COG4559; Bacteria.
DR HOGENOM; CLU_000604_1_11_3; -.
DR InParanoid; Q7NN36; -.
DR OMA; FHIDAEI; -.
DR OrthoDB; 1752365at2; -.
DR PhylomeDB; Q7NN36; -.
DR Proteomes; UP000000557; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS51261; HMUV; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Translocase; Transport.
FT CHAIN 1..275
FT /note="Hemin import ATP-binding protein HmuV"
FT /id="PRO_0000269595"
FT DOMAIN 2..242
FT /note="ABC transporter"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
FT BINDING 34..41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
SQ SEQUENCE 275 AA; 29493 MW; 5779672D80E87F4C CRC64;
MLKAAGIGVR LAGRWLLEQV NLEALPGEVL AVVGPNGAGK STLLKTLAGE IRPTRGSVSM
AGKALADWPA RERACVRAVL PQNSTLAFAF RVFEVVLMGR TPHSRGLEGE RDRQIAREAM
AAAGVAHLAE RLYPTLSGGE KQRVQLARVL AQIWEAPPDS PRYLLLDEPT ASLDLTHQHS
TLAVARNFAH RGAAVVTVLH DLNLAAQYAD RLALLKDGKL LVVGVPDIVL TPEWIETGFG
LQTLVMRHPR LGCPLVIPLG SASVLQPGEQ LAHGK
