ID   HMUV_NOCFA              Reviewed;         288 AA.
AC   Q5YVL8;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Hemin import ATP-binding protein HmuV {ECO:0000255|HAMAP-Rule:MF_01718};
DE            EC=7.6.2.- {ECO:0000255|HAMAP-Rule:MF_01718};
GN   Name=hmuV {ECO:0000255|HAMAP-Rule:MF_01718}; OrderedLocusNames=NFA_29260;
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
OX   NCBI_TaxID=247156;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152;
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC   -!- FUNCTION: Part of the ABC transporter complex HmuTUV involved in hemin
CC       import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HmuV),
CC       two transmembrane proteins (HmuU) and a solute-binding protein (HmuT).
CC       {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01718};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Heme (hemin)
CC       importer (TC 3.A.1.14.5) family. {ECO:0000255|HAMAP-Rule:MF_01718}.
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DR   EMBL; AP006618; BAD57773.1; -; Genomic_DNA.
DR   RefSeq; WP_011209458.1; NC_006361.1.
DR   AlphaFoldDB; Q5YVL8; -.
DR   SMR; Q5YVL8; -.
DR   STRING; 247156.NFA_29260; -.
DR   EnsemblBacteria; BAD57773; BAD57773; NFA_29260.
DR   GeneID; 61133647; -.
DR   KEGG; nfa:NFA_29260; -.
DR   eggNOG; COG4559; Bacteria.
DR   HOGENOM; CLU_000604_1_11_11; -.
DR   OMA; RYAWNGL; -.
DR   BioCyc; NFAR247156:NFA_RS14615-MON; -.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51261; HMUV; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Translocase; Transport.
FT   CHAIN           1..288
FT                   /note="Hemin import ATP-binding protein HmuV"
FT                   /id="PRO_0000269604"
FT   DOMAIN          31..269
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
FT   BINDING         68..75
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
SQ   SEQUENCE   288 AA;  30155 MW;  1A49756D688C394F CRC64;
     MSTDLDRPRL GSLFTRGHEL PTAPARGEIT LRARGLVVER RGGSGPARRV LDQVDFAVAA
     GEIVALVGPN GAGKSTLLAA LAGELTPAAG GVELDGHPLT HWSPLDMARR RAVLPQTHTV
     GFPFTAREVV AMGRAPWVRT PRADHDDDLI AAAMAAADVT HLAGRAFPTL SGGECARVAL
     ARVLAQDTPT LLLDEPTAAL DLGHQEAVLR LAADRARDGA AVVVVLHDLG IAAAYADRVA
     VLDSGRVAAD GPPRAVLTTD LLTRVYQHPV EVLDHPVTGA QLVLPVRN