ID   HMUV_STRCO              Reviewed;         280 AA.
AC   Q9RKQ4;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Hemin import ATP-binding protein HmuV {ECO:0000255|HAMAP-Rule:MF_01718};
DE            EC=7.6.2.- {ECO:0000255|HAMAP-Rule:MF_01718};
GN   Name=hmuV {ECO:0000255|HAMAP-Rule:MF_01718}; OrderedLocusNames=SCO2274;
GN   ORFNames=SCC75A.20;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- FUNCTION: Part of the ABC transporter complex HmuTUV involved in hemin
CC       import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HmuV),
CC       two transmembrane proteins (HmuU) and a solute-binding protein (HmuT).
CC       {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01718};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Heme (hemin)
CC       importer (TC 3.A.1.14.5) family. {ECO:0000255|HAMAP-Rule:MF_01718}.
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DR   EMBL; AL939112; CAB61720.1; -; Genomic_DNA.
DR   PIR; T50583; T50583.
DR   RefSeq; NP_626522.1; NC_003888.3.
DR   RefSeq; WP_011028243.1; NZ_VNID01000001.1.
DR   AlphaFoldDB; Q9RKQ4; -.
DR   SMR; Q9RKQ4; -.
DR   STRING; 100226.SCO2274; -.
DR   GeneID; 1097707; -.
DR   KEGG; sco:SCO2274; -.
DR   PATRIC; fig|100226.15.peg.2311; -.
DR   eggNOG; COG1120; Bacteria.
DR   HOGENOM; CLU_000604_1_11_11; -.
DR   InParanoid; Q9RKQ4; -.
DR   OMA; RYAWNGL; -.
DR   PhylomeDB; Q9RKQ4; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51261; HMUV; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Translocase; Transport.
FT   CHAIN           1..280
FT                   /note="Hemin import ATP-binding protein HmuV"
FT                   /id="PRO_0000269631"
FT   DOMAIN          26..260
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
FT   BINDING         59..66
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
SQ   SEQUENCE   280 AA;  29121 MW;  6C5F4860186F6CDF CRC64;
     MRGVKLPRLV PSRPVPPPPA APGEVLAAAG GLRVHLGGRP VLDGVDVEVR AGEVLALVGP
     NGAGKSTLLG ALAADVPAAE GVVRVHGRPV SDWSAPELAL RRAVLPQSAS LSFPFAVEEV
     VRMGRAPWAG GDRADEDEAA VAEAMARTEV AGFAGRPFSA LSGGERARVA LARVLAQRAP
     LLLLDEPTAA LDLRHQELVL RLCRERARAG DAVVVVLHDL ALAAAYADRV ALLRSGRIAA
     GGPPSEVFAQ GLLSEVYDQP VEVFPHPRTG ALLVVPHRSP