ID   HMUV_VIBA7              Reviewed;         260 AA.
AC   Q70YG7; F7YI33;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Hemin import ATP-binding protein HmuV {ECO:0000255|HAMAP-Rule:MF_01718};
DE            EC=7.6.2.- {ECO:0000255|HAMAP-Rule:MF_01718};
GN   Name=hmuV {ECO:0000255|HAMAP-Rule:MF_01718}; OrderedLocusNames=VAA_01383;
OS   Vibrio anguillarum (strain ATCC 68554 / 775) (Listonella anguillarum).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=882102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION IN HEMIN TRANSPORT.
RC   STRAIN=ATCC 68554 / 775 / H775-3;
RX   PubMed=15342586; DOI=10.1128/jb.186.18.6159-6167.2004;
RA   Mourino S., Osorio C.R., Lemos M.L.;
RT   "Characterization of heme uptake cluster genes in the fish pathogen Vibrio
RT   anguillarum.";
RL   J. Bacteriol. 186:6159-6167(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 68554 / 775;
RX   PubMed=21576332; DOI=10.1128/iai.05138-11;
RA   Naka H., Dias G.M., Thompson C.C., Dubay C., Thompson F.L., Crosa J.H.;
RT   "Complete genome sequence of the marine fish pathogen Vibrio anguillarum
RT   harboring the pJM1 virulence plasmid and genomic comparison with other
RT   virulent strains of V. anguillarum and V. ordalii.";
RL   Infect. Immun. 79:2889-2900(2011).
CC   -!- FUNCTION: Part of the ABC transporter complex HmuTUV involved in hemin
CC       import. Responsible for energy coupling to the transport system
CC       (Probable). {ECO:0000305|PubMed:15342586}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HmuV),
CC       two transmembrane proteins (HmuU) and a solute-binding protein (HmuT).
CC       {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01718}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01718}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Heme (hemin)
CC       importer (TC 3.A.1.14.5) family. {ECO:0000255|HAMAP-Rule:MF_01718}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAF25489.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AJ496544; CAF25489.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP002284; AEH33069.1; -; Genomic_DNA.
DR   RefSeq; WP_013856730.1; NC_015633.1.
DR   AlphaFoldDB; Q70YG7; -.
DR   SMR; Q70YG7; -.
DR   EnsemblBacteria; AEH33069; AEH33069; VAA_01383.
DR   KEGG; van:VAA_01383; -.
DR   PATRIC; fig|882102.3.peg.1483; -.
DR   eggNOG; COG4559; Bacteria.
DR   HOGENOM; CLU_000604_1_11_6; -.
DR   OMA; KALCQEI; -.
DR   Proteomes; UP000006800; Chromosome I.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51261; HMUV; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Translocase; Transport.
FT   CHAIN           1..260
FT                   /note="Hemin import ATP-binding protein HmuV"
FT                   /id="PRO_0000269635"
FT   DOMAIN          7..243
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
FT   BINDING         39..46
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01718"
SQ   SEQUENCE   260 AA;  28484 MW;  DCC0CAA12C8FAE67 CRC64;
     MSTTAAIQAS NISVTFGHRT ILDKIDIEIF SGQVTALLGP NGAGKSTLLK ILSGEISSTG
     KMAYFGVPQA LWQPNELAKH LAILPQQSTL SFPFIAQEVV ELGALPLNLS HQQVSEVALH
     YMQQTDISDR ANNLYPALSG GEKQRLHLAR VLTQLHHSGD KKILMLDEPT SALDLAHQHN
     TLRIARSLAH QEQCAVVVVL HDLNLAAQYA DRMVMLHNGK LVCDAPPWEA LNAERIEQVY
     GYSSLVAAHP TMDFPMVYPI