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HMU_HALWD
ID   HMU_HALWD               Reviewed;        9159 AA.
AC   Q18DN4;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Halomucin;
DE   Flags: Precursor;
GN   Name=hmu; OrderedLocusNames=HQ_1081A;
OS   Haloquadratum walsbyi (strain DSM 16790 / HBSQ001).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloquadratum.
OX   NCBI_TaxID=362976;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16790 / HBSQ001;
RX   PubMed=16820047; DOI=10.1186/1471-2164-7-169;
RA   Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F.,
RA   Pfeiffer F., Oesterhelt D.;
RT   "The genome of the square archaeon Haloquadratum walsbyi: life at the
RT   limits of water activity.";
RL   BMC Genomics 7:169-169(2006).
CC   -!- FUNCTION: May protect the organism from desiccation stress. May also
CC       contribute to the rigidity and maintenance of the unique square cell
CC       morphology of H.walsbyi.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- PTM: Probably glycosylated with sugar containing sialic acid. This may
CC       further contribute to its overall negative charge, thereby creating an
CC       aqueous shield covering the cells.
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DR   EMBL; AM180088; CAJ51211.1; -; Genomic_DNA.
DR   RefSeq; WP_011570378.1; NC_008212.1.
DR   SMR; Q18DN4; -.
DR   STRING; 362976.HQ_1081A; -.
DR   PRIDE; Q18DN4; -.
DR   EnsemblBacteria; CAJ51211; CAJ51211; HQ_1081A.
DR   GeneID; 4194131; -.
DR   KEGG; hwa:HQ_1081A; -.
DR   eggNOG; arCOG03439; Archaea.
DR   eggNOG; arCOG06233; Archaea.
DR   eggNOG; arCOG07534; Archaea.
DR   eggNOG; arCOG07873; Archaea.
DR   eggNOG; arCOG10954; Archaea.
DR   HOGENOM; CLU_222693_0_0_2; -.
DR   OMA; APDNVYV; -.
DR   Proteomes; UP000001975; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   Gene3D; 3.10.100.10; -; 2.
DR   InterPro; IPR001304; C-type_lectin-like.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR013784; Carb-bd-like_fold.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR011493; GLUG.
DR   InterPro; IPR006626; PbH1.
DR   Pfam; PF07581; Glug; 1.
DR   SMART; SM00112; CA; 1.
DR   SMART; SM00034; CLECT; 2.
DR   SMART; SM00710; PbH1; 13.
DR   SUPFAM; SSF49313; SSF49313; 1.
DR   SUPFAM; SSF49452; SSF49452; 2.
DR   SUPFAM; SSF56436; SSF56436; 2.
DR   PROSITE; PS50041; C_TYPE_LECTIN_2; 2.
DR   PROSITE; PS50268; CADHERIN_2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Lectin; Reference proteome; Repeat; Secreted; Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..9159
FT                   /note="Halomucin"
FT                   /id="PRO_0000259666"
FT   DOMAIN          644..776
FT                   /note="C-type lectin 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT   DOMAIN          929..1060
FT                   /note="C-type lectin 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT   DOMAIN          7686..7793
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00043"
FT   REGION          1310..1351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1756..3380
FT                   /note="V-G-G-L motif-rich region"
FT   REGION          3484..3514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          4878..4912
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          6570..6589
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          7047..7097
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          7660..7702
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          7888..7923
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          8212..8237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          8369..8614
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1310..1337
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3484..3499
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4890..4912
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7047..7081
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7901..7922
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8377..8458
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8472..8535
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8560..8614
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   9159 AA;  927738 MW;  2170B9429C2A41E7 CRC64;
     MSQTAKPIFA VVVALIVLIS GVAFIGSVSA QQPNLVQNGS FENSSNDFSS DNNYNTLVAD
     STAITGWRVS SGEVDQVGSY WSPQDGSVSI DLSGSEPGVI EQNVTGLEAG KRYELTYYYS
     GHRVQEGKYE AGVEIADLNI TETASSPGDW TLATHTFTAD STAETLTFTQ ITPSSGAKGM
     AIDNVSIVES SDPIDTAAPT VSVNQPAGGA TLTTSDVALN ASANETGNWT YSVDGGPNQT
     ATDANGTKTL NVTLSGLADG SHTATVYIKD DGGNIGIDTV SFTISSAPTV TTSSGGTNYT
     ASTGGFVVDE NLTVTNPDGG TIDGATIAIG SGFNASVDTL AIDEAVAPNN SITSTNYNGT
     TGVLTLDGTA SAAEMQTVLR TVTYAYSGET TASARDIDVS FALGTGGNNS STPTTAQITV
     TVSSDTTAPS VTIDQPVEGS TLTTGDVAFD ASANKTGNWT YSVDGDPNQT ATGANGTQTL
     NVTLSGLADG SHTATVYIKD DGGNVDTDTV SFTVSTASSL TTSSSKTDYT ASDGGFVVDD
     SLTVTSPDDT LINGATVAIG SGFDASEDTL AVNETVASNN NITNTNYNSA TGVLTLDGTA
     SADEMQTVLR TVTYTYSGDA TASARDLDVS FSLGTGGNIV FDPTTGNYYE LVSETVTWKT
     AKDEAENRSH LGLQGYLATL TSERENDETA SRFTFDKAWI GASDASTEGD WKWVTGPERG
     TLFWEGDESG SEQNGEYAGW ASTDPNAIQG ENYAFINQNL EWIDQKNGVN YNYLVEYGGL
     NGSSSPTAQR TVTVDTEAPT LTTSSGSVTN TTASGGYLVD DKLTVTDPDG GGIDTATVSI
     SQGFDPSADR LSVNTTLATN RGITSTYDDT TGVLNVSANS SATVTADDFQ AVLRTVTYNF
     TGTSVTNESD RTVPIRFALD ANQEQVTAYD GHYYEYVSDS VSFDTARSEA ENRSHLGLEG
     YLATLTSEQE DDTIHQQFDQ ESWIGASDAE TEGDWKWVTG PENGTLFWKD GSTQNGEYAG
     WEGGEPNSQN LDENYAEINF DDYTGWNDQV DNQGYLVEYG GLTTDSAITA QRNVTIDTGA
     PNVSNVTIRR IDGGGVVTTN DTIEVSATVT DVSSIQSVTA SAIAFDAGTV NLSDDGPNSS
     AADDVYSATF TVGPDPIEQT QSVTVTATDD AGNGGTPPGD LVYDSITVNP EGTTDFRTVR
     LPRSFENPVV IAKPLESTSS GNVAPDNRRG HTRIRNVQST SFEIRVEEWS VQDDEDHPAA
     NVSYIVAEAG TTTLDDSTKV SAGTITLNQN DGFQSITFEE SLNSPVAFTQ PQTVNDPDAV
     STRNNNVGSN GLDSKIEDDQ NNGADGNPHG TETLGYIAIE QGDSVLGETG FTAGTQGNVD
     ETLTSINFGD SYPAGFVAAM QTTGGTEQSY LRYDDRTDTG VRVRIEEDPV DNSDRHNSET
     VGYLAWNAST QVTGTRSNEL SVDTSAPQID DLSASFTTGS PPVSAGDEFR VTATVTDAGA
     VSTVEADVAA LDADPGTITL DDLGNDTYEG TFEVGQNPDP TRAVAVTVTD SLGNNASATT
     IAGSQASWDH EVNGTVQTGT FAGNGSAVDP YIIDSLVDLQ AINKNATTRA YNYRLGTDID
     ASTTRSWNDG KGFAPVGAVN GRDIGEPFSG SLDGDGYTIS NLSVDQRSTD TNALGLVGKL
     DSDGAVRNLT LANASVAGDD DIGAAVGKSA GTVRNVTVSG MVDGDQRIGG VVGTVTSTGT
     VTNTTAVANT SGNQGVGGLI GESSGTVNNA SAGGAVTATG QYAGGLIGDH QSSTAVTDVN
     ASGAVTGASY TGGLVGRGQA GVINASANGD VTSTTGEYVG GLVGQLQAQH GDEEVRNVTA
     SGNVSSGGQY VGGLIGDVRD DGTNYVAMSE AHATGNVNTT YADESGFNNA YVGGLVGHFK
     GSEFTDISAT GDVTSTTGNE VGGLVGRVAM EQERDIVANA SATGNVTTTG QRVGGLIGYH
     RTGTILRNVT ATGDVSTDGQ RVGGLVGDTD ASITDASATG EVTTSTSGEY VGGLVGQLQA
     QHGDEEVRNV TASGNVSSGG RYVGGLIGDV SDDGTHYVAM SEAHATGHVN TTYADESGFN
     NAYVGGLVGH FEGSEFTDIS ATGDVTSTAG NEVGGLVGRV AMEQERDIVA NASATGNVTT
     TGQRVGGLIG YHRTGTILRN VTATGDVSTD GQRVGGLVGD TDASITDASA TGEVTTSTTG
     EYVGGLVGQL RAQHGDEEVR NVTASGNVSS GGQYVGGLMG YVDDNNNRGR YVAMSEAHAT
     GNVNTTYADE SGFNNAYVGG LVGHFKGSEF TDISATGDVT STTGNEVGGL VGRVVMRNNG
     IVANASATGN VTTTGQRVGG LIGYHRTGTI LRNVTATGDV STDGQRVGGL VGDTDASITD
     ASATGEVTTS TTGEYVGGLV GQLRAQHGDE EVRNVTASGN VSSGGQYVGG LMGYVDDNNN
     EGRYVAMSEA HATGNVNTTY DGGSNAYVGG LVGRFKGSEF TDISATGDVT STTGNEVGGL
     VGRVAMRNNG IVANASATGN VTTTGQQIGG LIGYHQNGDG VETSYARGDV STDGNYVGGL
     IGDTNDGSIT DSYARGDVNS SGDYVGGLVG EANGDVTRAY ASGRVEGDGT DIGGLVGTNN
     GGTLSDAYWD RGATNQTAAT GSGTPPGATG YGTVGDTRAL EMQGRAPTQF MAALNYTSPW
     KLTSTYPIFQ RESATSGSLP ATVDTIEAST ATVVQTQQMT VKLNATINGS RVGPGYLITV
     SDSNGLAELE GQRALTDQNG TATFTFAEQS AGTFTPTFEA VSDLNVTATA TVEVNEGAAR
     TYIREDGTEL TAVYSGNGTV DDPYEIDSLA DLQAINNNTA ARDNHYELVA NIDTSATNNT
     SWNNGNGFEP ITEYTGSLDG NGRTISNLSI NRSGANGVGL VDTLGSEGTI QNLTIQNASI
     TGDNDLGVAV GINNGRVENV TASGTVSGND RIGGLVGTVN SGGVITASTA AATTSGSKSI
     GGLVGQNNGA VNNASASGTV TATGQYAGGL IGDHRSTISI VDTNASGAVT GTSSTGGLIG
     RAQANVTDSS ASGRVNGTTG SNVGGLIGEH DPSQVATIAN VSASGDVSTS GGVRVGGLVG
     SSISGSPVTM LNARAEGNVT TSDLSGTDAF TGGLIGEIQN AKNVTNVSAT GQVNASIAGN
     QVVTGRVGGL IGSFEHESAS RIVANASATG DVATDTNGQV GGLIGTYSGG GTVEDSNARG
     NVSATGQSVG GLLGSADASI IRRSSATGDV NSTGSNVGGL IGKHDPSQVA TIANVSASGN
     VSTRNQGAGG LVGAIQTSPV SISDAGASGD VTAAVGSGRG YVGGLIGEIR NAKNVTNVSA
     SGQVNVSANT GFNGEHVGGL IGVIDHESGA NIVANASATG DVNADAAGPT GGLIGGTEGT
     LGTVQDSYAQ GNVSGTGPVG GLIGQTNGDT ARVYASGRVE GNSGLGGLIG DNSGQISESY
     WDKGATAQSD ATGSGTPGGA TGYGSVGDTT PAPQMQGRAA TELMDGLHYT TTWNVTRGYP
     VLQAQSNGTE QPPRTVDTVT ATNASAIQSE QVSVSVTVTT AGTDTGTGTA AGLIVSAQDT
     GGLTSLNNAT AVTNETGTAT LTITESDTGT FSPTFTVVGY STATANATVT VSDGAVRTYV
     REDGEELTAV YSGNGTADNP YLIDSLADLQ AIDNSSAARA DNYRLAEDID ASATSDASWN
     DGSGFEPITP FTGSLDGNDT TISNLSINRS GASTAGLVGA LDSNGAIQNL TIQNASVTGS
     DELGVVAGTN DGTIQNLTVE DASIDGVNDL GVAVGTNNGT VQNVTASGAV RGSDRIGGLV
     GTVNSGGVVT DATTTATANG SQSIGGLVGE SNGAVNNASA SGTVTATDQY AGGLIGDHQS
     TTPVTDVNAS GAVTGTSYIG GLLGRGQADV INASAGGSVN GTSGGYVGGL IGQAKSSSGN
     PITVSNAHAS GVVNATNTGT DAYTGGLVGE FQNAGNVTDV SATGDVNASE PEGGNLVGGL
     FGELHHDSAD HILTNASATG DVDATGQRVG GLIGYYKDGD GVETSYARGN VSTDGDYVGG
     LIGDTNNDGS ITDSYARGDV TTSGDKVGGL VGETEDVDVT RSYASGRVKG GSTVGGLVGN
     NTGQLSGAYW DKGATNQTAA TGSGSSGGAT GFGTVGDDTQ ALEMQGRAPT QFMSALDYTS
     PWKLTSTYPV FQRESNTSGS LLAPVDTIEA TGTTAVQTQQ ITVEVNATIN GSPVGPGYLI
     NVSDSNGLAE LDSKTALTDA NGTATFTFAG PTAGTFEPEF EAVSNSAASA TATVTVESGA
     VRTFIREDGT ELTAVYRGNG TADSPYEVDS LADLQAIDNS TAAHGDQYTL VANIDASATD
     ESSWNGGGGF EPIANATDEA FTGTLNGNGH TISNLSVDRS GANRAGLVGT LGSNGTIQNL
     TIQNASITGN NDVGTAVGTS AGTIQNVTAS GTVNGNDRIG GVVGEVTADG LVTDSTASVN
     TSGNQAIGGL VGQSSGAVNN ASASGEVTAT SKYAGGLIGD HQSTTPVTDV NASGTVSGTS
     SAGGLIGRAQ ANVTDATATG DVVSTSGTKV GGLIGNHQAG QTIVDVSATG TVSSDGDDVG
     GLVGFTRASV RNATASGEVE STTGANVGGL VGRLSHDDST HVTNVTATGT VSAGADHVGG
     LVGFIEDSDD NGNITMSGAR ATGDIEMTSD DGGPASVGGL VGRFEHGSAI TDVSATGDVS
     SVGGNEVGGL IGRLDQLAST DVLKNASATG DVTTTGQKVG GLIGFHRTGS VDNSHAQGNV
     SAGSGDNVGG LIGVHGRNGG RVGDSYARGD VNTSGNNVGG LIGRSEGKVL RVYATGRVEG
     GSAVGGLVGK NDGGQLSESY WDKGATDKSD ATGSDTPATV SGYGSVGDTT PAPQMQGRAA
     TELMEGLNYT TTWNVTRGYP VLQAKSTGTE QLPRTVDTVT ATNASAIQSE QVSVSVTVTT
     TDSNIREDFV ISVQDTGGLT SLENATAVTN DTGVATFNIT ESSPDTYTPT FGVAGYSTAT
     VNATVTVDNG AVRTYTREDD TELTAVYRGN GTPDSPYLID TLADLQSINI DSGTRNEQYR
     LAADIDASAT NESSWNGGRG FEPITDFTGS LNGDGYAISN LSIDRGNEAS VGLFGDTNAG
     SSITNVTLVQ PAVTGGQGTG PLVGSHGGSI SRTVVTGGTA TTEADGEAHL GGLVGILVDD
     AKITQSHTSA IVDANGHNEA GGFAGDIGSN ARVEQVSATG GVKNGGSEIG GLFGNASSGS
     EIVEAFAAGN VSGTTNVGGL LGRQDGSAVT VDRAYWDEQS TGQTSSAGDT ETALPTVKMQ
     GTAATEFMPG LNFTTTWNTT RDYPVLQVQT TGTEQPPRTV DTIDATNASL VQSEQVSVSI
     TVTASEADSR NGFLISVQDA AGLTSLENAT AVTNETGTAA FNLTESDAGT FTPTFGVAGD
     ASATTNATLT VKQGAVRTYT REDGTALTAV YTGNGTPESP YEIDSLADLQ AIDNSSTARN
     NSYRLTADID ASATIESSWN DGSGFEPIAN ATDDDEAFTG SLDGDGHTIS NLSIDRSGAD
     TVGLFGELDT AGVLENVTLQ NASVTGGNDV GLVAGTSNGT LRNVTTTGTV TGNNRVGGLI
     GTTELNSVLT ESSAAVNTSG SQRVGGLVGT AGGIVNTSTA NGTVTATGQY AGGLIGESQG
     TIPVTNTAAS GNVTGTADVG GLIGRTNTTV RNSSASGVVN STSGDGVGGL IGRSLAAVHD
     SSASGAVSST GGNSVGGLIG NAGADVTNSA GRGNVISSTG NEVGGLVGRL EDSSNIRDSH
     ARGTVTAAGS DVGGLAGTID TGNATRVFAT GQVEGNSAVG GLVGKNNGGT LSDVYWDKGA
     TNQTNATGSA TPTGADGYGL VNDDTPAERM QGEAATAFMS ALNYTTTWNT TRGYPVLQAQ
     ATGTEQPPRR VETIDATDAS SAQTEQVAIS ITVTAADSES TDGFVITVRE SDGLSGLEDA
     TAVTDQDGTA TFSFSESNAN SYKPTFGVAG DTAVSTTANI TVKEGAVRTY TREDGTNLTG
     TYIGSGTPDD PYLANSLTDL QVINKNATTR DEHYQLTDDI NASATIESWN GGNGFEPIAN
     ATDEAFTGTL DGNGTTISNL SIDRSGADSV GLISEVGTSG VMENLTLQNA SVIGSNDVGV
     VAGTSNGTIR NVTATGTVAG DNKIGGLVGA SNSSAVVADS STAVTTSGTR QIGGLVGQSS
     GSVTNSSASG SVTASGGFAG GLVGDLDVTT PEELANVSAS GNVSSGGQYV GGLVGLGTST
     SSSGNQLTIT EAQASGDVNT TYNGGNDAYV GGLAGKLSNV GNVTDVTATG DVSSTSGNDV
     GGLAGELVHD STSFTLRNAT ATGDVTTTGQ RVGGLIGAHR NGQALTNATA TGNVSTDGNN
     VGGLIGYQPD DKTVSDVTAT GDVSTEGNNA GGLIGQTRAS LSDATASGEV QSSTGDKIGG
     LVGYLKLSAE KTTNVTATGN VSTDGNNVGG LIGHAEGVES TSQTTISTAR ASGDVTSTDG
     NDIGGLIGNA SFQNDADTVT NASATGDVGT DSATGSSVGG LIGSQSSGQV RNSYARGNVT
     TSGDNVGGLV GSAAGKQIVD SYARGNITTE GTNVGGIAGK LSGDVKRVYA SGQVTGDNKV
     GGLVGSGGTL SDAYWDKGAS TQTNATGNKS GLGTGTPNGV AGYGSIGSDV PATEMQGQSP
     SKFMSALNYT STWSLVNGYP QLRAETAPSF ASDTTPPTLT SVTSTDGTTI QLTIDGGVSG
     IDTSSIDNTD FAVSNNSILS TDTNTSGTDT NTTQTVTLSL SSSVETRPVT VDITSQAGGI
     TDRSGNKLSN ITTTLPGIDT VSVSDDTNDD GIVTTGDRVQ VTVESNTDTN TDTDTDTTLS
     SVTVNATDYD DETATLSPNG TNVETGASIH SGIIIVGSTP TDGSDQSLTV NVTDDTGNAA
     VRTIQVSGVT VDTKAPEITS VSRAGGDSVD VSIQSGLSGI EKSSISAADF TVEPGKVASV
     NTSAVTDGSN QTQTVRIGLT DAIRGKTPTV TINSSSDGIL DKAGNGQGED STSSNESSDG
     TESDQGDPED DIGGINTGIA PAVTLTTSDL DSSTLSTVDV TYNATGEVGS SDDIEIQLYN
     DNNSTTTPIA TRTVGSVEGL TSLTVPSSAV GGGTFTGRAT LVNTSAGNTE LANKSKQIVA
     YENVSTSVTA GSLGGKITVK HDFGSLDPAN AQIRVSPITI GSKFTTQTVT PAPAQKQGTV
     TIPVPKQANS RFNVQTEVVD TSRNRQIQSS LGYGCVGSQR DPCSTVSETG TTVVDATTGN
     SVGIEVNATV DHNRGAVEWY LHPTGSPEQK DISIVDGVDA STPLAVTIAV DDFDPVFMLG
     TGNADGWEKT GVDKNTKEIS INVTPAEAYV EPDIRNPDPR EWPLSDHTAS KRYGAIVDMI
     AVSMEGRVNP GYRNHLDGAF IGTNAQAFSV PKSSAGGSDS AGSLSITVAA PHYETDGTTV
     NTGFYNARIP KSVLAAWGIS PGQVTATYKG ESVSGSSLTV EDKKGAIFVS MPVTYSSGTV
     TVSGSQDSSD TTAPTVSNVS LDSDGTGNLT FTVDSNEQLG VATDNVSVSI DGPNTNDVYT
     FNRDDLIQSG SGPYTYALDL DSAQPYDNGG GTYTATVDTA TDSAGNDGGG SGLTDSHDHT
     VTGSTPTFVS SGTVTTPENP GGTLLDVNAI DGEGGLFDSG VKYTITGGAD SSSFTVDGKT
     GAVSFADSVD FESPADADGD NAYELDVTAS TANANATQSI SVTITDVDEQ PTGQVNLTGG
     DPGDRTISIV GNKTGYTFDA SKIVDPEGTG VSYTWDFGIG DTSTGSTVTR DYDPGSYLEE
     TTVSPTLTVD DGSKQTVIDV SVTFYSDIDG DGLADDNEAT GVPTDNDDDN DGIPDDEDQE
     PALGEMSSIS GTITDTNGSR VTQGDVTIIS SDGTHRESVS LDSNGKFDTT VPAGNYRLVV
     ENTSAPVHER EDITVGPQTP TSQNLTLEGS GTVAGKFINP DEKSASNIPV QIASRDGGET
     YYTKTDSTGE YEVAVEPGDY VVAPLGNDSG NASREVSVEL GETIQQSVTL DPQPVETAAS
     LSIASGPGSV TADGHQMVVI PEVTDGLLQI QIANNSDPNR DISVVEDPSE LENFGVTNET
     KFRIRVTVTN YTPHTLFWAL RDAEFNSKPN ATNPTATDII ITGSPVSLAT TSTQQKRVGP
     LVSEDPSTVS WPSGAADTAD SQYNQTVYFS VYDLSTRPES LRDRLTGLIL STNAQRISLP
     EVSNDRLRTW IAGPRYKTAS GTKYEGFYQA QIPQSQLEEW GVADHPTHQL FGEYKSSERN
     LTVEDVDGGI SVDVSNISYS ASYVDIKADS TAPVPESALE DDSSNQDSGD DSSNQDSGDD
     SSSQNDDGDN SSNQDSGDDS SSQNDDGDNS SNQDSGDDSS SQNDDGDNSS NQDSGDDSSS
     QNDDGDDSSS QNDDGDNSSN QDSGDDSSSQ NDDGDNSSNQ DSGDDSSSQN DDGDNSSNQD
     SGDDSSSQND DGDNKPNSAA AVGAESGSEM GGETGGESQA GGGDGSSGSS SDAAGGGSSG
     GSSSGDSGGS SSGNSGGSSS GNSGGSSSGS GSSTGSMIAD ALTVITAPLR WFGSLSTAGK
     AAVAATTGAG AAGAAYGLGG DRIQTPLNIA RRRFQSWLRR RIRGSSRSQI SKLLARLRRL
     KWAKIRTQIA GVRKYFTRSY WRELIAKRRR LGSREGMKNW LKSKYRGNRK RKYRGWLRGR
     LRSGVNWVAG GLLRGAAPAW LGVVSGPAAT AVSVITGEIR RWIEDKAMDR FDSTRKRYAK
     LAIQSSAWIT TVETRLWQLL SGEDSPSSSR SLAAIAGESA SELNEVGVDS VDQLASADPE
     QLASALEIDE SAVAEWVNRA GHASGSTERP AFIETRNGKR IQARYEQIAE IVQTGVSIPT
     ISVGSVHSIT DIGGRQLARV TGWLQGDVSS ILSGAFERIQ SFSCRLLYRV SIWIYGPSGA
     VESIDGIGPE YSDRLVQEGI TDVAVLSACS AERLSERINV SSSQTYRWIT QATAETPDTR
     GLHQRLVAGV VRVESVFIAM KTKSSVQLES NRLREDHFSS QPLSEKEMNQ LAVVGITTVS
     QLAAINPDRL GAGVGIDTKT AEEWVEMAQV YEMHLNNNS
 
 
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