ID   HNDLB_XENLA             Reviewed;         291 AA.
AC   Q6NU14;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein D-like-B;
DE            Short=hnRNP D-like B;
DE            Short=hnRNP DL-B;
GN   Name=hnrnpdl-b; Synonyms=hnrpdl-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a transcriptional regulator. Binds DNA and RNA (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O14979}. Cytoplasm
CC       {ECO:0000250|UniProtKB:O14979}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC068788; AAH68788.1; -; mRNA.
DR   RefSeq; NP_001084608.1; NM_001091139.1.
DR   AlphaFoldDB; Q6NU14; -.
DR   SMR; Q6NU14; -.
DR   DNASU; 414562; -.
DR   GeneID; 414562; -.
DR   KEGG; xla:414562; -.
DR   CTD; 414562; -.
DR   Xenbase; XB-GENE-6252556; hnrnpdl.S.
DR   OrthoDB; 1565323at2759; -.
DR   Proteomes; UP000186698; Chromosome 1S.
DR   Bgee; 414562; Expressed in gastrula and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd12758; RRM1_hnRPDL; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR034847; hnRPDL_RRM1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   Cytoplasm; DNA-binding; Methylation; Nucleus; Reference proteome; Repeat;
KW   RNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..291
FT                   /note="Heterogeneous nuclear ribonucleoprotein D-like-B"
FT                   /id="PRO_0000287244"
FT   DOMAIN          34..116
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          119..196
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          196..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   291 AA;  32956 MW;  C2ED6AB182B7ED96 CRC64;
     MELSEITRST LVSTLSRLLR RHKESNPDFF LIRSKMFIGG LSWDTSKKDL TEYLSRFGEV
     LDCTIKTDPV TGRSRGFGFV LFKDAVSVDK VLETKEHKLD GKLIDPKRAK ALQGKEPPKK
     VFVGGLSPET TEEQIKQYFG GFGEIENIEL PMDTKTNERR GFCFVTYTDE EPVQKLLESR
     FHQIGTGKCE IKAAQPKEVY RQQQQKQQKG GRGGTRGRGR GQGYSNYYDQ NYGGYGNNDS
     YGDQGYGGYD YSGYNYGNYG YNQGYTDYSG QQSTYGKARG GGNHQNNYQP Y