AOC4_ARATH
ID AOC4_ARATH Reviewed; 254 AA.
AC Q93ZC5; Q9FX69;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Allene oxide cyclase 4, chloroplastic;
DE EC=5.3.99.6;
DE Flags: Precursor;
GN Name=AOC4; OrderedLocusNames=At1g13280; ORFNames=T6J4.4, T6J4_23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, SUBCELLULAR LOCATION, AND
RP INDUCTION.
RC STRAIN=cv. Columbia; TISSUE=Leaf;
RX PubMed=12777050; DOI=10.1023/a:1023049319723;
RA Stenzel I., Hause B., Miersch O., Kurz T., Maucher H., Weichart H.,
RA Ziegler J., Feussner I., Wasternack C.;
RT "Jasmonate biosynthesis and the allene oxide cyclase family of Arabidopsis
RT thaliana.";
RL Plant Mol. Biol. 51:895-911(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Involved in the production of 12-oxo-phytodienoic acid
CC (OPDA), a precursor of jasmonic acid.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate =
CC (10Z,15Z)-12-oxophytodienoate; Xref=Rhea:RHEA:22592,
CC ChEBI:CHEBI:36438, ChEBI:CHEBI:57411; EC=5.3.99.6;
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:12777050}.
CC -!- TISSUE SPECIFICITY: Highly expressed in fully developed leaves.
CC {ECO:0000269|PubMed:12777050}.
CC -!- INDUCTION: Low local and systemic induction by wounding.
CC {ECO:0000269|PubMed:12777050}.
CC -!- MISCELLANEOUS: The four allene oxide cyclase proteins (AOC1, AOC2, AOC3
CC and AOC4) are encoded by duplicated genes. They are very similar, and
CC most experiments involving antibodies do not discriminate between the
CC different members.
CC -!- SIMILARITY: Belongs to the allene oxide cyclase family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG09557.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ308486; CAC83764.1; -; mRNA.
DR EMBL; AC011810; AAG09557.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28994.1; -; Genomic_DNA.
DR EMBL; AY141993; AAM98257.1; -; mRNA.
DR EMBL; AY057636; AAL15267.1; -; mRNA.
DR PIR; D86267; D86267.
DR RefSeq; NP_172786.1; NM_101199.4.
DR AlphaFoldDB; Q93ZC5; -.
DR SMR; Q93ZC5; -.
DR BioGRID; 23128; 1.
DR STRING; 3702.AT1G13280.1; -.
DR SwissPalm; Q93ZC5; -.
DR PaxDb; Q93ZC5; -.
DR PRIDE; Q93ZC5; -.
DR ProteomicsDB; 244470; -.
DR DNASU; 837888; -.
DR EnsemblPlants; AT1G13280.1; AT1G13280.1; AT1G13280.
DR GeneID; 837888; -.
DR Gramene; AT1G13280.1; AT1G13280.1; AT1G13280.
DR KEGG; ath:AT1G13280; -.
DR Araport; AT1G13280; -.
DR TAIR; locus:2205349; AT1G13280.
DR eggNOG; ENOG502QPP8; Eukaryota.
DR HOGENOM; CLU_069000_0_0_1; -.
DR InParanoid; Q93ZC5; -.
DR OMA; SFHNQRI; -.
DR OrthoDB; 1284108at2759; -.
DR PhylomeDB; Q93ZC5; -.
DR BioCyc; ARA:AT1G13280-MON; -.
DR BRENDA; 5.3.99.6; 399.
DR PRO; PR:Q93ZC5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q93ZC5; baseline and differential.
DR Genevisible; Q93ZC5; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0005576; C:extracellular region; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0046423; F:allene-oxide cyclase activity; ISS:TAIR.
DR GO; GO:0009695; P:jasmonic acid biosynthetic process; TAS:TAIR.
DR Gene3D; 2.40.480.10; -; 1.
DR InterPro; IPR009410; Allene_ox_cyc.
DR InterPro; IPR044859; Allene_oxi_cyc_Dirigent.
DR InterPro; IPR034871; Allene_oxi_cyc_sf.
DR PANTHER; PTHR31843; PTHR31843; 1.
DR Pfam; PF06351; Allene_ox_cyc; 1.
DR SUPFAM; SSF141493; SSF141493; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Isomerase; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..52
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 53..254
FT /note="Allene oxide cyclase 4, chloroplastic"
FT /id="PRO_0000001705"
SQ SEQUENCE 254 AA; 27809 MW; 4D82FA4889242353 CRC64;
MIMASSAAAS ISMITLRNLS RNHQSHQSTF LGFSRSFHNQ RISSNSPGLS TRARSTTSST
GGFFRTICSS SSNDYSRPTK IQELNVYEFN EGDRNSPAVL KLGKKPDQLC LGDLVPFTNK
LYTGDLTKRI GITAGLCVLI QHVPEKKGDR FEASYSFYFG DYGHISVQGP YLTYEDTFLA
ITGGSGVFEG AYGQVKLRQL VYPTKLFYTF YLKGVAADLP VELTGKHVEP SKEVKPAAEA
QATQPGATIA NFTN
