HNRDL_XENTR
ID HNRDL_XENTR Reviewed; 297 AA.
AC Q640A2;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Heterogeneous nuclear ribonucleoprotein D-like;
DE Short=hnRNP D-like;
DE Short=hnRNP DL;
GN Name=hnrnpdl; Synonyms=hnrpdl; ORFNames=TNeu073n10.1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Neurula;
RG Sanger Xenopus tropicalis EST/cDNA project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a transcriptional regulator. Binds DNA and RNA (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O14979}. Cytoplasm
CC {ECO:0000250|UniProtKB:O14979}. Note=Shuttles between the nucleus and
CC the cytoplasm in a TNPO1-dependent manner.
CC {ECO:0000250|UniProtKB:O14979}.
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DR EMBL; CR761892; CAJ82429.1; -; mRNA.
DR EMBL; BC082729; AAH82729.1; -; mRNA.
DR RefSeq; NP_001011015.1; NM_001011015.1.
DR AlphaFoldDB; Q640A2; -.
DR SMR; Q640A2; -.
DR STRING; 8364.ENSXETP00000028487; -.
DR PaxDb; Q640A2; -.
DR PRIDE; Q640A2; -.
DR Ensembl; ENSXETT00000027520; ENSXETP00000027520; ENSXETG00000023026.
DR GeneID; 496424; -.
DR KEGG; xtr:496424; -.
DR CTD; 9987; -.
DR Xenbase; XB-GENE-495016; hnrnpdl.
DR eggNOG; KOG0118; Eukaryota.
DR HOGENOM; CLU_012062_1_1_1; -.
DR InParanoid; Q640A2; -.
DR OMA; PEYCNGY; -.
DR OrthoDB; 1565323at2759; -.
DR PhylomeDB; Q640A2; -.
DR TreeFam; TF314808; -.
DR Proteomes; UP000008143; Chromosome 1.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000023026; Expressed in gastrula and 26 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008143; F:poly(A) binding; IBA:GO_Central.
DR GO; GO:0034046; F:poly(G) binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR CDD; cd12758; RRM1_hnRPDL; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR034847; hnRPDL_RRM1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; SSF54928; 2.
DR PROSITE; PS50102; RRM; 2.
PE 2: Evidence at transcript level;
KW Cytoplasm; DNA-binding; Methylation; Nucleus; Reference proteome; Repeat;
KW RNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..297
FT /note="Heterogeneous nuclear ribonucleoprotein D-like"
FT /id="PRO_0000287245"
FT DOMAIN 26..108
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 111..190
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 297 AA; 33058 MW; 05B03B56C5A27D23 CRC64;
MTGFGATPDF NEGSKINASK NQQDEGKMFI GGLSWDTSKK DLTEYLSRFG EVVDCTIKTD
PVTGRSRGFG FVLFKDAVSV DKVLETKEHK LDGKLIDPKR AKALKGKEPP KKVFVGGLSP
ETTEEQIKQY FGGFGEIENI ELPMDTKTNE RRGFCFVTYT GEEPVKKLLE SRFHQIGTGK
CEIKVAQPKE VYRQQQQKQQ KGGRGAATGR GGARGRGRGQ GWNQGYSNYY DQNYGSYGNN
GSYADQGYNN SYSGYDYSGY NYGSYGYNQG YTDYSGQQST YGKARGGGNH QNNYQPY
