ID   HOAE1_PSEU2             Reviewed;         914 AA.
AC   Q7PC62;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Effector protein hopAE1;
DE   AltName: Full=Type III effector holPsyAE;
GN   Name=hopAE1; Synonyms=holPsyAE; OrderedLocusNames=Psyr_4269;
OS   Pseudomonas syringae pv. syringae (strain B728a).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=205918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SUBCELLULAR LOCATION.
RX   PubMed=12615215; DOI=10.1016/s1369-5274(02)00004-8;
RA   Greenberg J.T., Vinatzer B.A.;
RT   "Identifying type III effectors of plant pathogens and analyzing their
RT   interaction with plant cells.";
RL   Curr. Opin. Microbiol. 6:20-28(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B728a;
RX   PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA   Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA   Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA   Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA   Kyrpides N.C., Ivanova N., Lindow S.E.;
RT   "Comparison of the complete genome sequences of Pseudomonas syringae pv.
RT   syringae B728a and pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12615215}.
CC       Note=Secreted via type III secretion system (TTSS). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the HopW family. {ECO:0000305}.
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DR   EMBL; BK000956; DAA00391.1; -; Genomic_DNA.
DR   EMBL; CP000075; AAY39299.1; -; Genomic_DNA.
DR   RefSeq; WP_011268930.1; NC_007005.1.
DR   RefSeq; YP_237337.1; NC_007005.1.
DR   AlphaFoldDB; Q7PC62; -.
DR   STRING; 205918.Psyr_4269; -.
DR   EnsemblBacteria; AAY39299; AAY39299; Psyr_4269.
DR   KEGG; psb:Psyr_4269; -.
DR   PATRIC; fig|205918.7.peg.4405; -.
DR   eggNOG; ENOG50338PH; Bacteria.
DR   HOGENOM; CLU_318813_0_0_6; -.
DR   OMA; NAIVAQP; -.
DR   PHI-base; PHI:995; -.
DR   Proteomes; UP000000426; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029378; T3SS_HopW1-1/HolPsyAE.
DR   Pfam; PF15457; HopW1-1; 1.
PE   3: Inferred from homology;
KW   Secreted.
FT   CHAIN           1..914
FT                   /note="Effector protein hopAE1"
FT                   /id="PRO_0000245646"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   914 AA;  97211 MW;  E29C3BA0FA0E923E CRC64;
     MMPSQITRSS HSSLPEVAPA SGDAAGVSEQ TPQQARTVAF FASGELAVAF GRTSTAPAQD
     SVRLLSALQR ELDKQQPSWP TVAQLCHSLA EVAKTEQGWH QLASEDQAPA PALKDLLERC
     IGRLADMPAS HASHDSLSLA CEGLRTARLH QSVARLTARP PALARAIPDL LALTHLDPET
     LGAEPPVVSS YTLFSHFVHT AKQRTAELND SLQRQPEAVV SLLRSHADTL NDLETLPGAL
     QALTENCQDA PACNELRELA EVVGALLQLL REHGILPRLE AISIEPGEAP APGHEAAEPR
     LTRSQALLKA GGNLVRKFDA YGALAPMDDK GLLALMRTPA PHLSPDQMHA FLNKHVLHLT
     QEQRDIVSNT PLPFAPEGDI EARCGMGFDE KLRLALANGS LVLSEEQLAR LGHLPSAATT
     TSDVVKTLLE KPSSALSEAE RDMLGAIVQA NGQGQLDAWR AHNEQLPAVL SRSGLPSDVK
     DELLSLNQSM NAELGTLKNG ASFKSRILAS PAMLLALAPL PLAVAFVSKD NSYSSSLVAH
     FTKNAVFMAG LMMNELTNAR TNVDHGLNRY FVTVLANAIV AQPTFARNEH LLEQVGFGIA
     TAVASGAATL GVFNRESIVA AFKLAKSKLS RQDTGNASIP EEDHLAVVRH FDVSEHFAQQ
     MKVATELYKQ DKSITDIMNS SLTYLGTKSS EFQARFESVD ALRAGLQLAE GERKADPDFY
     TKLGLVALTA SIGAALVMLM KSMVGKADYA ADGVWCVSEM LKLAMNPEVD MQKAVQVFKE
     IVGLNLVMTG FLGVNKVWNF LDKGIKGYAS GAAVLTAANL TLPGMVGEVA GAAAGKGLSY
     LTDKGKAAHQ AGRAAASWAG NYVGTSRLGS AVGTLQTAIP GRIAGGQVVA GLYDRFRYLT
     GSHPTPAQQA AGEP