ID   HOATZ_BOVIN             Reviewed;         168 AA.
AC   Q32P68;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Cilia- and flagella-associated protein HOATZ {ECO:0000250|UniProtKB:Q80Y73};
GN   Name=HOATZ;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for motile ciliogenesis and flagellar genesis by
CC       mediating the maturation of the glycolytic enzyme ENO4.
CC       {ECO:0000250|UniProtKB:Q80Y73}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q80Y73}. Cell
CC       projection, cilium {ECO:0000250|UniProtKB:Q80Y73}.
CC   -!- SIMILARITY: Belongs to the HOATZ family. {ECO:0000305}.
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DR   EMBL; BC108238; AAI08239.1; -; mRNA.
DR   RefSeq; NP_001070496.1; NM_001077028.2.
DR   RefSeq; XP_005215928.1; XM_005215871.3.
DR   RefSeq; XP_005215929.1; XM_005215872.3.
DR   AlphaFoldDB; Q32P68; -.
DR   SMR; Q32P68; -.
DR   STRING; 9913.ENSBTAP00000045643; -.
DR   PaxDb; Q32P68; -.
DR   PRIDE; Q32P68; -.
DR   Ensembl; ENSBTAT00000048644; ENSBTAP00000045643; ENSBTAG00000034338.
DR   Ensembl; ENSBTAT00000081696; ENSBTAP00000069629; ENSBTAG00000034338.
DR   GeneID; 767960; -.
DR   KEGG; bta:767960; -.
DR   CTD; 399949; -.
DR   VEuPathDB; HostDB:ENSBTAG00000034338; -.
DR   VGNC; VGNC:54859; HOATZ.
DR   eggNOG; ENOG502S8UY; Eukaryota.
DR   GeneTree; ENSGT00390000002677; -.
DR   HOGENOM; CLU_122904_0_0_1; -.
DR   InParanoid; Q32P68; -.
DR   OMA; MYPPNES; -.
DR   OrthoDB; 1614119at2759; -.
DR   TreeFam; TF328616; -.
DR   Proteomes; UP000009136; Chromosome 15.
DR   Bgee; ENSBTAG00000034338; Expressed in olfactory segment of nasal mucosa and 43 other tissues.
DR   ExpressionAtlas; Q32P68; baseline.
DR   GO; GO:0005929; C:cilium; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0035082; P:axoneme assembly; ISS:UniProtKB.
DR   GO; GO:0060271; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0030317; P:flagellated sperm motility; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   InterPro; IPR040681; HOATZ-like.
DR   PANTHER; PTHR47231; PTHR47231; 1.
DR   Pfam; PF17664; HOATZ-like; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cytoplasm; Reference proteome.
FT   CHAIN           1..168
FT                   /note="Cilia- and flagella-associated protein HOATZ"
FT                   /id="PRO_0000328994"
FT   REGION          142..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        149..168
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   168 AA;  19218 MW;  C49F6A30B38C1497 CRC64;
     METRPSSSLS SPEESCEAFP QGLLVFTGSS DRDANLAKQF WIGASMYPHN ESQLVLSRGS
     SQRLPVARPS RSSAPEKTYF QPFFLEESKS RDVTAETLKI QESEEKKKYL QKAKKRDEII
     QLLRKQREER ILKELISLPH KPKGKVHKAK KVISESDKED QEEVKALD