ID   AOFH_MYCTU              Reviewed;         454 AA.
AC   P9WQ15; L0TDC6; O53320; P63533;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Putative flavin-containing monoamine oxidase AofH;
DE            EC=1.4.3.-;
GN   Name=aofH; OrderedLocusNames=Rv3170; ORFNames=MTV014.14;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the flavin monoamine oxidase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCP45981.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AL123456; CCP45981.1; ALT_INIT; Genomic_DNA.
DR   PIR; H70947; H70947.
DR   RefSeq; NP_217686.1; NC_000962.3.
DR   AlphaFoldDB; P9WQ15; -.
DR   SMR; P9WQ15; -.
DR   STRING; 83332.Rv3170; -.
DR   PaxDb; P9WQ15; -.
DR   DNASU; 888754; -.
DR   GeneID; 888754; -.
DR   KEGG; mtu:Rv3170; -.
DR   TubercuList; Rv3170; -.
DR   eggNOG; COG1231; Bacteria.
DR   OMA; PIHWAGT; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005829; C:cytosol; HDA:MTBBASE.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR001613; Flavin_amine_oxidase.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   PRINTS; PR00757; AMINEOXDASEF.
DR   SUPFAM; SSF51905; SSF51905; 1.
PE   1: Evidence at protein level;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome.
FT   CHAIN           1..454
FT                   /note="Putative flavin-containing monoamine oxidase AofH"
FT                   /id="PRO_0000099867"
SQ   SEQUENCE   454 AA;  49136 MW;  6C1AEB97FB2F435F CRC64;
     MRLTRAVTNP PWTVDVVVVG AGFAGLAAAR ELTRQGHEVL VFEGRDRVGG RSLTGRVAGV
     PADMGGSFIG PTQDAVLALA TELGIPTTPT HRDGRNVIQW RGSARSYRGT IPKLSLTGLI
     DIGRLRWQFE RIARGVPVAA PWDARRAREL DDVSLGEWLR LVRATSSSRN LMAIMTRVTW
     GCEPDDVSML HAARYVRAAG GLDRLLDVKN GAQQDRVPGG TQQIAQAAAA QLGARVLLNA
     AVRRIDRHGA GVTVTSDQGQ AEAGFVIVAI PPAHRVAIEF DPPLPPEYQQ LAHHWPQGRL
     SKAYAAYSTP FWRASGYSGQ ALSDEAPVFI TFDVSPHADG PGILMGFVDA RGFDSLPIEE
     RRRDALRCFA SLFGDEALDP LDYVDYRWGT EEFAPGGPTA AVPPGSWTKY GHWLREPVGP
     IHWASTETAD EWTGYFDGAV RSGQRAAAEV AALL