ID   HOFB_ECOLI              Reviewed;         461 AA.
AC   P36645; P75649; Q47022;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 3.
DT   03-AUG-2022, entry version 144.
DE   RecName: Full=Protein transport protein HofB homolog;
GN   Name=hofB; Synonyms=hopB; OrderedLocusNames=b0107, JW0103;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=7959070; DOI=10.1016/0378-1119(94)90851-6;
RA   Whitchurch C.B., Mattick J.S.;
RT   "Escherichia coli contains a set of genes homologous to those involved in
RT   protein secretion, DNA uptake and the assembly of type-4 fimbriae in other
RT   bacteria.";
RL   Gene 150:9-15(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8202364; DOI=10.1093/nar/22.9.1637;
RA   Fujita N., Mori H., Yura T., Ishihama A.;
RT   "Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-
RT   4.1 min (110,917-193,643 bp) region.";
RL   Nucleic Acids Res. 22:1637-1639(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND SEQUENCE REVISION.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   PRELIMINARY NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-283.
RC   STRAIN=K12;
RA   Bhatia R.S.;
RL   Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases.
RN   [6]
RP   IDENTIFICATION.
RA   Rudd K.R.;
RL   Unpublished observations (JAN-1994).
CC   -!- SIMILARITY: Belongs to the GSP E family. {ECO:0000305}.
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DR   EMBL; L28105; AAC36924.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC73218.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAB96676.2; -; Genomic_DNA.
DR   EMBL; L20834; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; C64733; C64733.
DR   RefSeq; NP_414649.1; NC_000913.3.
DR   RefSeq; WP_001025145.1; NZ_LN832404.1.
DR   AlphaFoldDB; P36645; -.
DR   SMR; P36645; -.
DR   BioGRID; 4261684; 8.
DR   DIP; DIP-9919N; -.
DR   IntAct; P36645; 5.
DR   STRING; 511145.b0107; -.
DR   PaxDb; P36645; -.
DR   PRIDE; P36645; -.
DR   EnsemblBacteria; AAC73218; AAC73218; b0107.
DR   EnsemblBacteria; BAB96676; BAB96676; BAB96676.
DR   GeneID; 947481; -.
DR   KEGG; ecj:JW0103; -.
DR   KEGG; eco:b0107; -.
DR   PATRIC; fig|511145.12.peg.109; -.
DR   EchoBASE; EB2030; -.
DR   eggNOG; COG2804; Bacteria.
DR   HOGENOM; CLU_013446_2_2_6; -.
DR   InParanoid; P36645; -.
DR   OMA; NMGVPAF; -.
DR   PhylomeDB; P36645; -.
DR   BioCyc; EcoCyc:EG12106-MON; -.
DR   PRO; PR:P36645; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001482; T2SS/T4SS.
DR   InterPro; IPR007831; T2SS_GspE_N.
DR   Pfam; PF00437; T2SSE; 1.
DR   Pfam; PF05157; T2SSE_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00662; T2SP_E; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Transport.
FT   CHAIN           1..461
FT                   /note="Protein transport protein HofB homolog"
FT                   /id="PRO_0000207305"
FT   BINDING         222..229
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        8..9
FT                   /note="AL -> EM (in Ref. 1; AAC36924)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        35
FT                   /note="H -> L (in Ref. 1; AAC36924)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        457..461
FT                   /note="MPHGE -> DAAWQ (in Ref. 1; AAC36924)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   461 AA;  50615 MW;  3E3A72AB05760255 CRC64;
     MNIPQLTALC LRYHGVLLDA SEEVVHVAVV DAPSHELLDA LHFATTKRIE ITCWTRQQME
     GHASRTQQTL PVAVQEKHQP KAELLTRTLQ SALEQRASDI HIEPADNAYR IRLRIDGVLH
     PLPDVSPDAG VALTARLKVL GNLDIAEHRL PQDGQFTVEL AGNAVSFRIA TLPCRGGEKV
     VLRLLQQVGQ ALDVNTLGMQ PLQLADFAHA LQQPQGLVLV TGPTGSGKTV TLYSALQKLN
     TADINICSVE DPVEIPIAGL NQTQIHPRAG LTFQGVLRAL LRQDPDVIMI GEIRDGETAE
     IAIKAAQTGH LVLSTLHTNS TCETLVRLQQ MGVARWMLSS ALTLVIAQRL VRKLCPHCRR
     QQGEPIHIPD NVWPSPLPHW QAPGCVHCYH GFYGRTALFE VLPITPVIRQ LISANTDVES
     LETHARQAGM RTLFENGCLA VEQGLTTFEE LIRVLGMPHG E