HOFC_HAEIN
ID HOFC_HAEIN Reviewed; 406 AA.
AC P44621;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Protein transport protein HofC homolog;
GN Name=hofC; Synonyms=hopC; OrderedLocusNames=HI_0297;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GSP F family. {ECO:0000305}.
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DR EMBL; L42023; AAC21961.1; -; Genomic_DNA.
DR PIR; D64060; D64060.
DR RefSeq; NP_438464.1; NC_000907.1.
DR RefSeq; WP_005694369.1; NC_000907.1.
DR AlphaFoldDB; P44621; -.
DR SMR; P44621; -.
DR STRING; 71421.HI_0297; -.
DR EnsemblBacteria; AAC21961; AAC21961; HI_0297.
DR KEGG; hin:HI_0297; -.
DR PATRIC; fig|71421.8.peg.313; -.
DR eggNOG; COG1459; Bacteria.
DR HOGENOM; CLU_035032_0_1_6; -.
DR OMA; IYRTFNT; -.
DR PhylomeDB; P44621; -.
DR BioCyc; HINF71421:G1GJ1-315-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015628; P:protein secretion by the type II secretion system; IBA:GO_Central.
DR Gene3D; 1.20.81.30; -; 2.
DR InterPro; IPR003004; GspF/PilC.
DR InterPro; IPR001992; T2SS_GspF/T4SS_PilC_CS.
DR InterPro; IPR018076; T2SS_GspF_dom.
DR InterPro; IPR042094; T2SS_GspF_sf.
DR PANTHER; PTHR30012; PTHR30012; 1.
DR Pfam; PF00482; T2SSF; 2.
DR PRINTS; PR00812; BCTERIALGSPF.
DR PROSITE; PS00874; T2SP_F; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..406
FT /note="Protein transport protein HofC homolog"
FT /id="PRO_0000207846"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 406 AA; 46291 MW; 429D83B7C10F8F82 CRC64;
MTKKLFYYQA SNPLNQKQKG SIIADTKQQA HFQLISRGLT HIKLQQNWQF GAKPKNSEIS
ELLNQLATLL QSAIPLKNSL QILQQNCTQI VLNEWLERLL QSIESGLAFS QAIEQQGKYL
TQQEIQLIQV GEMTGKLAVV CKKIATHRSQ SLALQRKLQK IMLYPSMVLG ISLLLTLALL
LFIVPQFAEM YSGNNAELPT ITAILLSISN FLKQNIGILL FFVLSFFLFY YFYLKRQTWF
YQKKNQLISI TPIFGTIQKL SRLVNFSQSL QIMLQAGVPL NQALDSFLPR TQTWQTKKTL
VNDIVLDKEV RSILQWVSQG YAFSNSVSSD LFPMEAQQML QIGEQSGKLA LMLEHIAENY
QEKLNHQIDL LSQMLEPLMM VIIGSLIGII MMGMYLPIFN MGSVIQ