ID   HOPW1_PSEYM             Reviewed;         774 AA.
AC   Q8RP17;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Effector protein hopW1-1;
DE   AltName: Full=Type III effector hopPmaA;
GN   Name=hopW1-1; Synonyms=hopPmaA; ORFNames=PMA4326B12;
OS   Pseudomonas syringae pv. maculicola.
OG   Plasmid pPMA4326B.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=59511;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBCELLULAR LOCATION.
RC   STRAIN=ES4326;
RX   PubMed=11872842; DOI=10.1126/science.295.5560.1722;
RA   Guttman D.S., Vinatzer B.A., Sarkar S.F., Ranall M.V., Kettler G.,
RA   Greenberg J.T.;
RT   "A functional screen for the type III (Hrp) secretome of the plant pathogen
RT   Pseudomonas syringae.";
RL   Science 295:1722-1726(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ES4326; PLASMID=pPMA4326B;
RX   PubMed=15262947; DOI=10.1128/jb.186.15.5101-5115.2004;
RA   Stavrinides J., Guttman D.S.;
RT   "Nucleotide sequence and evolution of the five-plasmid complement of the
RT   phytopathogen Pseudomonas syringae pv. maculicola ES4326.";
RL   J. Bacteriol. 186:5101-5115(2004).
RN   [3]
RP   INTERACTION WITH ARABIDOPSIS WIN1; WIN2 AND WIN3.
RX   PubMed=18266921; DOI=10.1111/j.1365-313x.2008.03439.x;
RA   Lee M.W., Jelenska J., Greenberg J.T.;
RT   "Arabidopsis proteins important for modulating defense responses to
RT   Pseudomonas syringae that secrete HopW1-1.";
RL   Plant J. 54:452-465(2008).
CC   -!- FUNCTION: Induces hypersensitive response (HR).
CC       {ECO:0000269|PubMed:11872842}.
CC   -!- SUBUNIT: Interacts (via C-terminus) with Arabidopsis WIN1, WIN2 and
CC       WIN3. {ECO:0000269|PubMed:18266921}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11872842}.
CC       Note=Secreted via type III secretion system (TTSS).
CC   -!- SIMILARITY: Belongs to the HopW family. {ECO:0000305}.
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DR   EMBL; AF458040; AAL84239.1; -; Genomic_DNA.
DR   EMBL; AY603980; AAT35179.1; -; Genomic_DNA.
DR   RefSeq; WP_011178595.1; NZ_LGLD01000064.1.
DR   RefSeq; YP_025680.1; NC_005919.1.
DR   AlphaFoldDB; Q8RP17; -.
DR   SMR; Q8RP17; -.
DR   GeneID; 64468642; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0051701; P:biological process involved in interaction with host; IDA:UniProtKB.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   InterPro; IPR029378; T3SS_HopW1-1/HolPsyAE.
DR   Pfam; PF15457; HopW1-1; 1.
PE   1: Evidence at protein level;
KW   Hypersensitive response elicitation; Plasmid; Secreted.
FT   CHAIN           1..774
FT                   /note="Effector protein hopW1-1"
FT                   /id="PRO_0000239715"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          301..340
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   774 AA;  83957 MW;  36381511F0C111AA CRC64;
     MSPAQIIRTP HSFPPSFTGT SSSAENSHAQ SPQQVLTRAF VASGELNAAF GRTSTASEQD
     FTSLLGTLQR ELERKTLSFP DIAELANQLA EAAKGDQGGH WLGRDEQQTL KGMIDRCKSQ
     LAHTHASDAS YDPLAQVCEN LKTARLHQSI SQMTGEAHAK VRGVPDLLAL IQLDPDVLAE
     KPVGMTSYVN FGSFICMAKA RTAELSEDLR SDPNEVALLL HPHADTILEL ERLPDALAAL
     TENCPDTPTR DDLRSLAKET GELLQQLRAN DLLPRSEEVS SYQGETSVRS REVVEPKLTL
     CQAGGNGQGQ LEASSARPES LRYAPTRAAS SGSEARVPGQ AVGGKIADDA QKVAGLYAEK
     KRTNWTQANG VAGKISHKIQ SLLGMRDAGS RVQAFVAFMA DGKGRPGATM LDLGDGWMRA
     TRVIKGEAAL IDFQCDSDGK VVDARHPGRF PVLPQGNERE AFKTVLQELK FRGAETLSKV
     PVYYVNRNTR GYVIPTHGYV VAGHPNRGRK SGAVLYGVGG DPKRGPVALD EKLLGHLVGR
     SDSKTSSKLS APVKAAISAL AGASFATRED FYDAYCAVRG DAVDPLERHN EISSIYRLLP
     LSTMEMWPKK ADDYRVARPA APERDLRAFE NLPKDIGRKA QLKKVSNVDS IDLLEAKRQF
     TLHQLYQDEM LGRNGTGVPS ADFKPKVDAQ RRDQLVASTP KFQRLPPHTT DKVGNCNTGA
     SSLLQRAVDT YTEKNNLPPE KVTAASIFGI GSSHRLAIWD PLDGSSSNKS SKDR