AOTP_PSEAE
ID AOTP_PSEAE Reviewed; 254 AA.
AC O30506; Q9I556;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Arginine/ornithine transport ATP-binding protein AotP;
GN Name=aotP; OrderedLocusNames=PA0892;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=9791103; DOI=10.1128/jb.180.21.5559-5566.1998;
RA Nishijyo T., Park S.-M., Lu C.-D., Itoh Y., Abdelal A.T.;
RT "Molecular characterization and regulation of an operon encoding a system
RT for transport of arginine and ornithine and the ArgR regulatory protein in
RT Pseudomonas aeruginosa.";
RL J. Bacteriol. 180:5559-5566(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 161-254.
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=9286980; DOI=10.1128/jb.179.17.5300-5308.1997;
RA Park S.-M., Lu C.-D., Abdelal A.T.;
RT "Cloning and characterization of argR, a gene that participates in
RT regulation of arginine biosynthesis and catabolism in Pseudomonas
RT aeruginosa PAO1.";
RL J. Bacteriol. 179:5300-5308(1997).
CC -!- FUNCTION: Part of the arginine-inducible binding-protein-dependent
CC transport system for arginine and ornithine. Probably responsible for
CC energy coupling to the transport system.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; AF012537; AAC71074.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG04281.1; -; Genomic_DNA.
DR EMBL; AF008308; AAC45652.1; -; Genomic_DNA.
DR PIR; T44458; T44458.
DR RefSeq; NP_249583.1; NC_002516.2.
DR RefSeq; WP_003085940.1; NZ_QZGE01000007.1.
DR AlphaFoldDB; O30506; -.
DR SMR; O30506; -.
DR STRING; 287.DR97_1051; -.
DR TCDB; 3.A.1.3.11; the atp-binding cassette (abc) superfamily.
DR PaxDb; O30506; -.
DR PRIDE; O30506; -.
DR EnsemblBacteria; AAG04281; AAG04281; PA0892.
DR GeneID; 882247; -.
DR KEGG; pae:PA0892; -.
DR PATRIC; fig|208964.12.peg.927; -.
DR PseudoCAP; PA0892; -.
DR HOGENOM; CLU_000604_1_22_6; -.
DR InParanoid; O30506; -.
DR OMA; EVFCLIG; -.
DR PhylomeDB; O30506; -.
DR BioCyc; PAER208964:G1FZ6-908-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015424; F:ABC-type amino acid transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR030679; ABC_ATPase_HisP-typ.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR PIRSF; PIRSF039085; ABC_ATPase_HisP; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; ATP-binding; Cell inner membrane; Cell membrane;
KW Membrane; Nucleotide-binding; Reference proteome; Transport.
FT CHAIN 1..254
FT /note="Arginine/ornithine transport ATP-binding protein
FT AotP"
FT /id="PRO_0000091930"
FT DOMAIN 4..249
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 36..43
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 254 AA; 27956 MW; E25D6EB07B496B3D CRC64;
MYKLEVQDLH KRYGSHEVLK GVSLAAKAGD VISIIGSSGS GKSTFLRCIN LLEQPHAGKI
LLNGEELKLV PGRDGALKAA DSRQLQRMRS RLSMVFQHFN LWSHMSALEN VIEAPVHVLG
VSKKEAIEKA EHYLAKVGVA HRKDAYPAHM SGGEQQRVAI ARALAVEPEV MLFDEPTSAL
DPELVGEVLK VMQDLAQEGR TMVVVTHEMG FAREVSNQLV FLHKGLVEEH GCPKEVLANP
QSDRLKQFLS GSLK
