HOX18_ORYSJ
ID HOX18_ORYSJ Reviewed; 256 AA.
AC Q5Z6F6; A0A0P0X0H4;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Homeobox-leucine zipper protein HOX18;
DE AltName: Full=HD-ZIP protein HOX18;
DE AltName: Full=Homeodomain transcription factor HOX18;
DE AltName: Full=OsHox18;
GN Name=HOX18; OrderedLocusNames=Os06g0698200, LOC_Os06g48290;
GN ORFNames=OsJ_021636, P0028E05.36;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [4]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17999151; DOI=10.1007/s11103-007-9255-7;
RA Agalou A., Purwantomo S., Oevernaes E., Johannesson H., Zhu X., Estiati A.,
RA de Kam R.J., Engstroem P., Slamet-Loedin I.H., Zhu Z., Wang M., Xiong L.,
RA Meijer A.H., Ouwerkerk P.B.F.;
RT "A genome-wide survey of HD-Zip genes in rice and analysis of drought-
RT responsive family members.";
RL Plant Mol. Biol. 66:87-103(2008).
CC -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaf sheaths and blades and
CC panicles. {ECO:0000269|PubMed:17999151}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class II subfamily.
CC {ECO:0000305}.
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DR EMBL; AP005445; BAD54463.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS99304.1; -; Genomic_DNA.
DR EMBL; CM000143; EAZ38153.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5Z6F6; -.
DR SMR; Q5Z6F6; -.
DR STRING; 39947.Q5Z6F6; -.
DR PaxDb; Q5Z6F6; -.
DR PRIDE; Q5Z6F6; -.
DR EnsemblPlants; Os06t0698200-00; Os06t0698200-00; Os06g0698200.
DR Gramene; Os06t0698200-00; Os06t0698200-00; Os06g0698200.
DR eggNOG; KOG0483; Eukaryota.
DR HOGENOM; CLU_049516_3_0_1; -.
DR InParanoid; Q5Z6F6; -.
DR OMA; EDSFRVH; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000007752; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR Genevisible; Q5Z6F6; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR003106; Leu_zip_homeo.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00340; HALZ; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..256
FT /note="Homeobox-leucine zipper protein HOX18"
FT /id="PRO_0000331709"
FT DNA_BIND 112..171
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 52..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..214
FT /note="Leucine-zipper"
FT COMPBIAS 52..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 256 AA; 27591 MW; 3218A34B1F401803 CRC64;
MEGEDLGSWL GLGIGGGGYA YGGDDCRRSP SSPSPVQMLF SQHVKEEITR GYDHGRDEEQ
ASGSKIMKGE RGARLRVMRS IRNSGGDGSR SRVLSLGDDG GDGGSGGGGG GGTRKKLQLT
KEQSTLLEDS FRVHNILSHA QKHELARQLK LKPRQVEVWF QNRRARTKLK QTEVDCEFLK
RCCESLTEEN KQLKHELMEL RRLASPAAAA AGSQLYVQFP RAAAAAMVNV CPSCEKVTVM
GGGGGETGKS SSSYSS
