HOX1A_MAIZE
ID HOX1A_MAIZE Reviewed; 719 AA.
AC P46605;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Homeobox protein HOX1A;
GN Name=HOX1A;
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Shoot;
RX PubMed=1354614; DOI=10.1002/j.1460-2075.1992.tb05415.x;
RA Bellmann R., Werr W.;
RT "Zmhox1a, the product of a novel maize homeobox gene, interacts with the
RT Shrunken 26 bp feedback control element.";
RL EMBO J. 11:3367-3374(1992).
CC -!- FUNCTION: Interacts with the shrunken (SHR) 26 bp feedback control
CC element.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- TISSUE SPECIFICITY: Expressed in kernels, leaves and shoots but not in
CC roots.
CC -!- SIMILARITY: Belongs to the PHD-associated homeobox family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X67561; CAA47859.1; -; mRNA.
DR PIR; S25237; S25237.
DR RefSeq; NP_001105447.1; NM_001111977.1.
DR AlphaFoldDB; P46605; -.
DR SMR; P46605; -.
DR STRING; 4577.GRMZM2G136369_P01; -.
DR PaxDb; P46605; -.
DR PRIDE; P46605; -.
DR EnsemblPlants; Zm00001eb353320_T001; Zm00001eb353320_P001; Zm00001eb353320.
DR GeneID; 542406; -.
DR Gramene; Zm00001eb353320_T001; Zm00001eb353320_P001; Zm00001eb353320.
DR KEGG; zma:542406; -.
DR MaizeGDB; 25707; -.
DR eggNOG; KOG4299; Eukaryota.
DR OMA; THEYHSG; -.
DR OrthoDB; 536362at2759; -.
DR Proteomes; UP000007305; Chromosome 8.
DR ExpressionAtlas; P46605; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR CDD; cd15504; PHD_PRHA_like; 1.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR045876; PRHA-like_PHD-finger.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF57903; SSF57903; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..719
FT /note="Homeobox protein HOX1A"
FT /id="PRO_0000049143"
FT ZN_FING 209..266
FT /note="PHD-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00146"
FT DNA_BIND 559..618
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 302..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 612..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..354
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..483
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..642
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..678
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..719
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 719 AA; 79116 MW; 5536608CA71CB318 CRC64;
MEKNIAHCPV EGNGEIENGA SSSQNPESLE HSVLLSTSQT MPNNLGIRKN YKRAANRGKK
GSQGLTGQAY TLMSSNSDVR VLRSTSSSKT TSTEHVQAPV QPAAKRRKMS RASNKSSTDE
FSQIRKRVRY ILNRMNYEQS LIEAYASEGW KNQSLDKIRP EKELERAKSE ILRCKLRIRE
VFRNIDSLLS KGKIDETLFD SEGEISCEDI FCSTCGSNDA TLGNDIILCD GACDRGFHQN
CLNPPLRTED IPMGDEGWLC PACDCKIDCI DLINELHGSN ISIEDSWEKV FPDAAAMAND
SKQDDAFDLP SDDSDDNDFD PNMPEEHVVG KDEESSEEDE DGGSDSDDSD FLTCSDDSEP
LIDKKVDDLR LPSEDSEDDD YDPAGPDSDK DVEKKSSSDE SDFTSDSDDF CKEISKSGHD
EVSSPLLPDA KVGDMEKITA QAKTTSSADD PMETEIDQGV VLPDSRRRQA ERLDYKKLYD
EAYGEASSDS SDDEEWSGKN TPIIKSNEEG EANSPAGKGS RVVHHNDELT TQSTKKSLHS
IHGSVDEKPG DLTSNGSNST ARKGHFGPVI NQKLHEHFKT QPYPSRSVKE SLAEELGLTF
RQVNKWFETR RHSARVASSR KGISLDKHSP QNTNSQVTAS MEPKEPEGTV VEESNVCLNG
GTTISKEAVS SKVGSRTPGS DVGGSKVDSA EDQNPGPDLA EKARQKAIQQ ELRKKKMGR
