HOX1_ORYSI
ID HOX1_ORYSI Reviewed; 311 AA.
AC Q40691; A2ZA87; A5JPT8;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 127.
DE RecName: Full=Homeobox-leucine zipper protein HOX1;
DE AltName: Full=HD-ZIP protein HOX1;
DE AltName: Full=Homeodomain transcription factor HOX1;
DE AltName: Full=OsHox1;
GN Name=HOX1; ORFNames=OsI_033480;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBUNIT, AND TISSUE SPECIFICITY.
RC STRAIN=cv. IR58; TISSUE=Etiolated seedling;
RX PubMed=9076993; DOI=10.1046/j.1365-313x.1997.11020263.x;
RA Meijer A.H., Scarpella E., van Dijk E.L., Qin L., Taal A.J.C., Rueb S.,
RA Harrington S.E., McCouch S.R., Schilperoort R.A., Hoge J.H.C.;
RT "Transcriptional repression by Oshox1, a novel homeodomain leucine zipper
RT protein from rice.";
RL Plant J. 11:263-276(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, TISSUE SPECIFICITY, AND
RP INDUCTION.
RC STRAIN=cv. IR58;
RX PubMed=10934011; DOI=10.1242/dev.127.17.3655;
RA Scarpella E., Rueb S., Boot K.J.M., Hoge J.H.C., Meijer A.H.;
RT "A role for the rice homeobox gene Oshox1 in provascular cell fate
RT commitment.";
RL Development 127:3655-3669(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 111-249, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Minghui 86;
RX PubMed=17999151; DOI=10.1007/s11103-007-9255-7;
RA Agalou A., Purwantomo S., Oevernaes E., Johannesson H., Zhu X., Estiati A.,
RA de Kam R.J., Engstroem P., Slamet-Loedin I.H., Zhu Z., Wang M., Xiong L.,
RA Meijer A.H., Ouwerkerk P.B.F.;
RT "A genome-wide survey of HD-Zip genes in rice and analysis of drought-
RT responsive family members.";
RL Plant Mol. Biol. 66:87-103(2008).
RN [5]
RP FUNCTION, AND SUBUNIT.
RX PubMed=10732669; DOI=10.1007/pl00008671;
RA Meijer A.H., de Kam R.J., d'Erfurth I., Shen W.-B., Hoge J.H.C.;
RT "HD-Zip proteins of families I and II from rice: interactions and
RT functional properties.";
RL Mol. Gen. Genet. 263:12-21(2000).
CC -!- FUNCTION: Probable transcription repressor involved leaf development.
CC Binds to the DNA sequence 5'-CAAT[GC]ATTG-3'. May act as a regulatory
CC switch to specify provascular cell fate. {ECO:0000269|PubMed:10732669,
CC ECO:0000269|PubMed:10934011, ECO:0000269|PubMed:9076993}.
CC -!- SUBUNIT: Homodimer (Probable). May form a heterodimer with HOX2, HOX3
CC or HOX7. {ECO:0000269|PubMed:10732669, ECO:0000269|PubMed:9076993,
CC ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in root provascular and vascular
CC cylinder, provascular and vascular strands of leaves, provascular and
CC vascular strands of the whole panicle, in mature embryo provascular
CC bundles of scutellum and embryonic axis and provascular and vascular
CC strands of young immature spikelet organs. Expressed in differentiating
CC and differentiated xylem and phloem elements, and in outer and inner
CC bundle sheath cells of all vascular bundles. Expressed in auricles,
CC ligules, culm, guard cells brac hairs and pollen.
CC {ECO:0000269|PubMed:10934011, ECO:0000269|PubMed:17999151,
CC ECO:0000269|PubMed:9076993}.
CC -!- INDUCTION: By auxin and sucrose in primary root apical region. By
CC wounding in leaves. {ECO:0000269|PubMed:10934011}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class II subfamily.
CC {ECO:0000305}.
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DR EMBL; X96681; CAA65456.2; -; mRNA.
DR EMBL; AF211193; AAF19980.1; -; Genomic_DNA.
DR EMBL; CM000135; EAY79521.1; -; Genomic_DNA.
DR EMBL; EF555521; ABQ57264.1; -; mRNA.
DR PIR; T03775; T03775.
DR AlphaFoldDB; Q40691; -.
DR SMR; Q40691; -.
DR STRING; 39946.Q40691; -.
DR EnsemblPlants; BGIOSGA033443-TA; BGIOSGA033443-PA; BGIOSGA033443.
DR Gramene; BGIOSGA033443-TA; BGIOSGA033443-PA; BGIOSGA033443.
DR HOGENOM; CLU_049516_2_0_1; -.
DR OMA; SHMHMQS; -.
DR Proteomes; UP000007015; Chromosome 10.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR006712; HD-ZIP_N.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR003106; Leu_zip_homeo.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF04618; HD-ZIP_N; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00340; HALZ; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..311
FT /note="Homeobox-leucine zipper protein HOX1"
FT /id="PRO_0000331674"
FT DNA_BIND 154..213
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 29..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..256
FT /note="Leucine-zipper"
FT REGION 279..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 311 AA; 33044 MW; C7098BB1640B5CFF CRC64;
MEMMVHGRRD EQYGGLGLGL GLGLSLGVAG GAADDEQPPP RRGAAPPPQQ QLCGWNGGGL
FSSSSSDHRG RSAMMACHDV IEMPFLRGID VNRAPAAETT TTTARGPSCS EEDEEPGASS
PNSTLSSLSG KRGAPSAATA AAAAASDDED SGGGSRKKLR LSKDQAAVLE DTFKEHNTLN
PKQKAALARQ LNLKPRQVEV WFQNRRARTK LKQTEVDCEL LKRCCETLTD ENRRLHRELQ
ELRALKLATA AAAPHHLYGA RVPPPTTLTM CPSCERVASA ATTTRNNSGA APARPVPTRP
WPPAAAQRSS A
