HOX1_ORYSJ
ID HOX1_ORYSJ Reviewed; 311 AA.
AC Q7XC54; B7EAV9; Q9AUT0;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Homeobox-leucine zipper protein HOX1;
DE AltName: Full=HD-ZIP protein HOX1;
DE AltName: Full=Homeodomain transcription factor HOX1;
DE AltName: Full=OsHox1;
GN Name=HOX1; OrderedLocusNames=Os10g0561800, LOC_Os10g41230;
GN ORFNames=OsJ_031189, OSJNBb0089A17.12;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12791992; DOI=10.1126/science.1083523;
RA Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP FUNCTION, SUBUNIT, AND TISSUE SPECIFICITY.
RX PubMed=9076993; DOI=10.1046/j.1365-313x.1997.11020263.x;
RA Meijer A.H., Scarpella E., van Dijk E.L., Qin L., Taal A.J.C., Rueb S.,
RA Harrington S.E., McCouch S.R., Schilperoort R.A., Hoge J.H.C.;
RT "Transcriptional repression by Oshox1, a novel homeodomain leucine zipper
RT protein from rice.";
RL Plant J. 11:263-276(1997).
RN [8]
RP FUNCTION, SUBUNIT, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=10732669; DOI=10.1007/pl00008671;
RA Meijer A.H., de Kam R.J., d'Erfurth I., Shen W.-B., Hoge J.H.C.;
RT "HD-Zip proteins of families I and II from rice: interactions and
RT functional properties.";
RL Mol. Gen. Genet. 263:12-21(2000).
RN [9]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17999151; DOI=10.1007/s11103-007-9255-7;
RA Agalou A., Purwantomo S., Oevernaes E., Johannesson H., Zhu X., Estiati A.,
RA de Kam R.J., Engstroem P., Slamet-Loedin I.H., Zhu Z., Wang M., Xiong L.,
RA Meijer A.H., Ouwerkerk P.B.F.;
RT "A genome-wide survey of HD-Zip genes in rice and analysis of drought-
RT responsive family members.";
RL Plant Mol. Biol. 66:87-103(2008).
CC -!- FUNCTION: Probable transcription repressor involved leaf development.
CC Binds to the DNA sequence 5'-CAAT[GC]ATTG-3'. May act as a regulatory
CC switch to specify provascular cell fate. {ECO:0000269|PubMed:10732669,
CC ECO:0000269|PubMed:9076993}.
CC -!- SUBUNIT: Homodimer (Probable). May form a heterodimer with HOX2, HOX3
CC or HOX7. {ECO:0000269|PubMed:10732669, ECO:0000269|PubMed:9076993,
CC ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in root provascular and vascular
CC cylinder, provascular and vascular strands of leaves, provascular and
CC vascular strands of the whole panicle, in mature embryo provascular
CC bundles of scutellum and embryonic axis and provascular and vascular
CC strands of young immature spikelet organs. Expressed in differentiating
CC and differentiated xylem and phloem elements, and in outer and inner
CC bundle sheath cells of all vascular bundles. Expressed in auricles,
CC ligules, culm, guard cells brac hairs and pollen.
CC {ECO:0000269|PubMed:10732669, ECO:0000269|PubMed:17999151,
CC ECO:0000269|PubMed:9076993}.
CC -!- INDUCTION: By auxin and sucrose in primary root apical region. By
CC wounding in leaves. {ECO:0000269|PubMed:10732669}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class II subfamily.
CC {ECO:0000305}.
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DR EMBL; AC079890; AAK31270.1; -; Genomic_DNA.
DR EMBL; DP000086; AAP55020.1; -; Genomic_DNA.
DR EMBL; AP008216; BAF27226.1; -; Genomic_DNA.
DR EMBL; AP014966; BAT12064.1; -; Genomic_DNA.
DR EMBL; CM000147; EAZ16980.1; -; Genomic_DNA.
DR EMBL; AK065404; BAG89506.1; -; mRNA.
DR RefSeq; XP_015613269.1; XM_015757783.1.
DR AlphaFoldDB; Q7XC54; -.
DR SMR; Q7XC54; -.
DR STRING; 4530.OS10T0561800-01; -.
DR PaxDb; Q7XC54; -.
DR PRIDE; Q7XC54; -.
DR EnsemblPlants; Os10t0561800-01; Os10t0561800-01; Os10g0561800.
DR GeneID; 4349388; -.
DR Gramene; Os10t0561800-01; Os10t0561800-01; Os10g0561800.
DR KEGG; osa:4349388; -.
DR eggNOG; KOG0483; Eukaryota.
DR HOGENOM; CLU_049516_2_0_1; -.
DR InParanoid; Q7XC54; -.
DR OMA; SHMHMQS; -.
DR OrthoDB; 1351830at2759; -.
DR Proteomes; UP000000763; Chromosome 10.
DR Proteomes; UP000007752; Chromosome 10.
DR Proteomes; UP000059680; Chromosome 10.
DR Genevisible; Q7XC54; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR006712; HD-ZIP_N.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR003106; Leu_zip_homeo.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF04618; HD-ZIP_N; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00340; HALZ; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..311
FT /note="Homeobox-leucine zipper protein HOX1"
FT /id="PRO_0000331675"
FT DNA_BIND 154..213
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 29..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..256
FT /note="Leucine-zipper"
FT REGION 279..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 311 AA; 33143 MW; 670D95016400EBF9 CRC64;
MEMMVHGRRD EQYGGLRLGL GLGLSLGVAG GAADDEQPPP RRGAAPPPQQ QLCGWNGGGL
FSSSSSDHRG RSAMMACHDV IEMPFLRGID VNRAPAAETT TTTARGPSCS EEDEEPGASS
PNSTLSSLSG KRGAPSAATA AAAAASDDED SGGGSRKKLR LSKDQAAVLE DTFKEHNTLN
PKQKAALARQ LNLKPRQVEV WFQNRRARTK LKQTEVDCEL LKRCCETLTD ENRRLHRELQ
ELRALKLATA AAAPHHLYGA RVPPPTTLTM CPSCERVASA ATTTRNNSGA APARPVPTRP
WPPAAAQRSS A
