HOX5_ORYSI
ID HOX5_ORYSI Reviewed; 350 AA.
AC Q9XH36; A2YV84; A5JPU2;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Homeobox-leucine zipper protein HOX5;
DE AltName: Full=HD-ZIP protein HOX5;
DE AltName: Full=Homeodomain transcription factor HOX5;
DE AltName: Full=OsHox5;
GN Name=HOX5; ORFNames=OsI_028227;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBUNIT, AND TISSUE SPECIFICITY.
RC STRAIN=cv. IR58; TISSUE=Seed embryo;
RX PubMed=10732669; DOI=10.1007/pl00008671;
RA Meijer A.H., de Kam R.J., d'Erfurth I., Shen W.-B., Hoge J.H.C.;
RT "HD-Zip proteins of families I and II from rice: interactions and
RT functional properties.";
RL Mol. Gen. Genet. 263:12-21(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 1-132, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Minghui 86;
RX PubMed=17999151; DOI=10.1007/s11103-007-9255-7;
RA Agalou A., Purwantomo S., Oevernaes E., Johannesson H., Zhu X., Estiati A.,
RA de Kam R.J., Engstroem P., Slamet-Loedin I.H., Zhu Z., Wang M., Xiong L.,
RA Meijer A.H., Ouwerkerk P.B.F.;
RT "A genome-wide survey of HD-Zip genes in rice and analysis of drought-
RT responsive family members.";
RL Plant Mol. Biol. 66:87-103(2008).
CC -!- FUNCTION: Probable transcription activator that binds to the DNA
CC sequence 5'-CAAT[AT]ATTG-3'. {ECO:0000269|PubMed:10732669}.
CC -!- SUBUNIT: Homodimer (Probable). May form a heterodimer with HOX4.
CC {ECO:0000269|PubMed:10732669, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, leaves, nodes,
CC internodes, flowers and embryo. {ECO:0000269|PubMed:10732669,
CC ECO:0000269|PubMed:17999151}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC {ECO:0000305}.
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DR EMBL; AF145729; AAD37698.1; -; mRNA.
DR EMBL; CM000133; EAZ06995.1; -; Genomic_DNA.
DR EMBL; EF555525; ABQ57268.1; -; mRNA.
DR AlphaFoldDB; Q9XH36; -.
DR SMR; Q9XH36; -.
DR STRING; 39946.Q9XH36; -.
DR EnsemblPlants; BGIOSGA026973-TA; BGIOSGA026973-PA; BGIOSGA026973.
DR Gramene; BGIOSGA026973-TA; BGIOSGA026973-PA; BGIOSGA026973.
DR HOGENOM; CLU_060842_2_0_1; -.
DR OMA; SCESAYF; -.
DR Proteomes; UP000007015; Chromosome 8.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR045224; HDZip_class_I_plant.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR InterPro; IPR003106; Leu_zip_homeo.
DR PANTHER; PTHR24326; PTHR24326; 1.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..350
FT /note="Homeobox-leucine zipper protein HOX5"
FT /id="PRO_0000331682"
FT DNA_BIND 83..142
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 141..185
FT /note="Leucine-zipper"
FT REGION 180..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 37444 MW; 5AC16B9877BE99F2 CRC64;
MDPGRVVFDS GVARRACPGG AQMLLFGGGG SANSGGFFRG VPAAVLGMDE SRSSSSAAGA
GAKRPFFTTH EELLEEEYYD EQAPEKKRRL TAEQVQMLER SFEEENKLEP ERKTELARRL
GMAPRQVAVW FQNRRARWKT KQLEHDFDRL KAAYDALAAD HHALLSDNDR LRAQVISLTE
KLQDKETSPS SATITTAAQE VDQPDEHTEA ASTTGFATVD GALAAPPPGH QQPPHKDDLV
SSGGTNDDGD GGGAAVVVFD VTEGANDRLS CESAYFADAA EAYERDCAGH YALSSEEEDG
GAVSDEGCSF DLPDAAAAAA AMFGAAGVVH HDAADDEEAQ LGSWTAWFWS
